Literature DB >> 10843490

Influence of diastereomeric ratios of deoxyribonucleoside phosphoramidites on the synthesis of phosphorothioate oligonucleotides.

Z S Cheruvallath1, H Sasmor, D L Cole, V T Ravikumar.   

Abstract

Extensive investigations on the influence of diastereomeric ratios of deoxyribonucleoside phosphoramidites on stereo-reproducibility of solid phase synthesis of phosphorothioate oligodeoxyribonucleotides via the phosphoramidite approach indicate that the process is stereoreproducible and under inherent process control.

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Year:  2000        PMID： 10843490     DOI： 10.1080/15257770008035005

Source DB:  PubMed          Journal:  Nucleosides Nucleotides Nucleic Acids        ISSN： 1525-7770            Impact factor:   1.381


  4 in total

1.  A nucleotide-independent nitroxide probe reports on site-specific stereomeric environment in DNA.

Authors:  Anna M Popova; Peter Z Qin
Journal:  Biophys J       Date:  2010-10-06       Impact factor: 4.033

2.  Synthesis, biophysical properties and biological activity of second generation antisense oligonucleotides containing chiral phosphorothioate linkages.

Authors:  W Brad Wan; Michael T Migawa; Guillermo Vasquez; Heather M Murray; Josh G Nichols; Hans Gaus; Andres Berdeja; Sam Lee; Christopher E Hart; Walt F Lima; Eric E Swayze; Punit P Seth
Journal:  Nucleic Acids Res       Date:  2014-11-14       Impact factor: 16.971

3.  Stereochemical bias introduced during RNA synthesis modulates the activity of phosphorothioate siRNAs.

Authors:  Hartmut Jahns; Martina Roos; Jochen Imig; Fabienne Baumann; Yuluan Wang; Ryan Gilmour; Jonathan Hall
Journal:  Nat Commun       Date:  2015-03-06       Impact factor: 14.919

4.  Synthesis of dinucleoside acylphosphonites by phosphonodiamidite chemistry and investigation of phosphorus epimerization.

Authors:  William H Hersh
Journal:  Beilstein J Org Chem       Date:  2015-01-30       Impact factor: 2.883
  4 in total

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