| Literature DB >> 10843226 |
M L López-Rodríguez1, E Porras, B Benhamú, J A Ramos, M J Morcillo, J L Lavandera.
Abstract
In order to make the first contribution to the elucidation of essential structural features for 5-HT7 antagonism, a set of thirty 5-HT7 antagonists were selected from the literature. A pharmacophore model was built using Molecular Modeling studies with Catalyst program. The information contained in this model was validated with new synthesized compounds.Mesh：
Substances：
Year: 2000 PMID： 10843226 DOI： 10.1016/s0960-894x(00)00166-9
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823