Literature DB >> 10843207

The first synthesis of clausenamine-A and cytotoxic activities of three biscarbazole analogues against cancer cells.

A Zhang1, G Lin.   

Abstract

Clausemine-A (3), isolated from the stem and root bark of Clausena excavata, was synthesized using Suzuki cross-coupling and Oxidative coupling as the key step. Compound 3, and the other two structurally related biscarbazoles 1 and 2, showed potent cytotoxic activities against a variety of human cancer cell lines in vitro.

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Year:  2000        PMID: 10843207     DOI: 10.1016/s0960-894x(00)00158-x

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  2 in total

1.  Site-Selective Aerobic C-H Monoacylation of Carbazoles Using Palladium Catalysis.

Authors:  Subhadip Maiti; Tirtha Mandal; Barada Prasanna Dash; Jyotirmayee Dash
Journal:  J Org Chem       Date:  2020-12-31       Impact factor: 4.198

2.  Efficient and simple synthesis of 6-aryl-1,4-dimethyl-9H-carbazoles.

Authors:  Anna Caruso; Anne Sophie Voisin-Chiret; Jean-Charles Lancelot; Maria Stefania Sinicropi; Antonio Garofalo; Sylvain Rault
Journal:  Molecules       Date:  2008-06-11       Impact factor: 4.411

  2 in total

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