Literature DB >> 10842101

Rapid genotype analysis of the matrix metalloproteinase-1 gene 1G/2G polymorphism that is associated with risk of cancer.

L Dunleavey1, S Beyzade, S Ye.   

Abstract

A bi-allelic polymorphism in the promoter of the human matrix metalloproteinase-1 gene has been reported. It has been found to have a functional effect on the promoter strength and to be associated with risk of cancers. The polymorphism is due to an insertion/deletion of a guanine, and conventional methodologies for genotyping this polymorphism are time-consuming and expensive. A rapid genotyping method based on restriction endonuclease digestion is reported here.

Entities:  

Mesh：

Substances：

Year:  2000        PMID： 10842101     DOI： 10.1016/s0945-053x(00)00059-7

Source DB:  PubMed          Journal:  Matrix Biol        ISSN： 0945-053X            Impact factor:   11.583


  9 in total

1.  Loss of heterozygosity on chromosome 11q22-23 in melanoma is associated with retention of the insertion polymorphism in the matrix metalloproteinase-1 promoter.

Authors:  W W Noll; D R Belloni; J L Rutter; C A Storm; A R Schned; L Titus-Ernstoff; M S Ernstoff; C E Brinckerhoff
Journal:  Am J Pathol       Date:  2001-02       Impact factor: 4.307

2.  Polymorphisms of the IL-1beta and IL-1beta-inducible genes in ulcerative colitis.

Authors:  Hiroaki Nohara; Yuki Saito; Singo Higaki; Naoko Okayama; Yuichiro Hamanaka; Kiwamu Okita; Yuji Hinoda
Journal:  J Gastroenterol       Date:  2002-11       Impact factor: 7.527

3.  Association of MMP1-1607 1G/2G and TIMP1 372 T/C gene polymorphisms with risk of primary open angle glaucoma in a Polish population.

Authors:  Ireneusz Majsterek; Lukasz Markiewicz; Karolina Przybylowska; Mira Gacek; Anna K Kurowska; Anna Kaminska; Jerzy Szaflik; Jacek P Szaflik
Journal:  Med Sci Monit       Date:  2011-07

4.  Genetic polymorphisms and the risk of myocardial infarction in patients under 45 years of age.

Authors:  Agata Sakowicz; Wojciech Fendler; Malgorzata Lelonek; Bartosz Sakowicz; Tadeusz Pietrucha
Journal:  Biochem Genet       Date:  2012-12-30       Impact factor: 1.890

5.  Genetic variability and the risk of myocardial infarction in Poles under 45 years of age.

Authors:  Agata Sakowicz; Wojciech Fendler; Malgorzata Lelonek; Tadeusz Pietrucha
Journal:  Arch Med Sci       Date:  2010-04-30       Impact factor: 3.318

6.  Genetic susceptibility of early aseptic loosening after total hip arthroplasty: the influence of TIMP-1 gene polymorphism on Chinese Han population.

Authors:  Fengyu Pan; Shan Hua; Yi Luo; Dongjun Yin; Zhuang Ma
Journal:  J Orthop Surg Res       Date:  2014-12-03       Impact factor: 2.359

Review 7.  Matrix metalloproteinase gene polymorphisms and oral cancer.

Authors:  Andresa C Pereira; Elaine Dias do Carmo; Marco A Dias da Silva; Luiz E Blumer Rosa
Journal:  J Clin Exp Dent       Date:  2012-12-01

8.  Genetic susceptibility to total hip arthroplasty failure: a case-control study on the influence of MMP 1 gene polymorphism.

Authors:  Yiguo Yan; Jianzhong Hu; Hongbin Lu; Wenjun Wang
Journal:  Diagn Pathol       Date:  2014-09-26       Impact factor: 2.644

9.  Intrinsic genetic characteristics determine tumor-modifying capacity of fibroblasts: matrix metalloproteinase-3 5A/5A genotype enhances breast cancer cell invasion.

Authors:  Deborah L Holliday; Simon Hughes; Jacqueline A Shaw; Rosemary A Walker; J Louise Jones
Journal:  Breast Cancer Res       Date:  2007       Impact factor: 6.466
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.