Literature DB >> 10837926

Detection of the interleukin 18 family in rat brain by RT-PCR.

R D Wheeler1, A C Culhane, M D Hall, S Pickering-Brown, N J Rothwell, G N Luheshi.   

Abstract

Interleukin 18, an inflammatory cytokine, mediates its effects by interaction with its receptor complex, consisting of the IL-18 receptor (IL-18R) and receptor accessory protein (AcPL). A functional inhibitor of IL-18, the IL-18 binding protein (IL-18BP), has been identified recently. This study reports the detection of IL-18, IL-18R, AcPL and IL-18BP mRNA expression in the brain of normal adult rats using RT-PCR.

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Year:  2000        PMID： 10837926     DOI： 10.1016/s0169-328x(00)00069-3

Source DB:  PubMed          Journal:  Brain Res Mol Brain Res        ISSN： 0169-328X


  14 in total

1.  Effect of hydrodynamics-based delivery of IL-18BP fusion gene on rat experimental autoimmune myocarditis.

Authors:  He Chang; Yan Wang; Gang Li; Le Zhang; Guang Wei Zhang; Yan Chun Liao; Haruo Hanawa; Jun Zou
Journal:  Clin Exp Med       Date:  2014-11       Impact factor: 3.984

2.  Interleukin-18 null mutation increases weight and food intake and reduces energy expenditure and lipid substrate utilization in high-fat diet fed mice.

Authors:  Eric P Zorrilla; Bruno Conti
Journal:  Brain Behav Immun       Date:  2013-12-06       Impact factor: 7.217

3.  Central nervous system cytokine gene expression: modulation by lead.

Authors:  Jane Kasten-Jolly; Yong Heo; David A Lawrence
Journal:  J Biochem Mol Toxicol       Date:  2011 Jan-Feb       Impact factor: 3.642

4.  Glial expression of interleukin-18 and its receptor after excitotoxic damage in the mouse hippocampus.

Authors:  Gye Sun Jeon; Sung Kyung Park; Sang Wook Park; Dong Woon Kim; Chun Kee Chung; Sa Sun Cho
Journal:  Neurochem Res       Date:  2007-08-22       Impact factor: 3.996

Review 5.  The expanding interleukin-1 family and its receptors: do alternative IL-1 receptor/signaling pathways exist in the brain?

Authors:  Herve Boutin; Ian Kimber; Nancy J Rothwell; Emmanuel Pinteaux
Journal:  Mol Neurobiol       Date:  2003-06       Impact factor: 5.590

Review 6.  Interleukin 18 in the CNS.

Authors:  Silvia Alboni; Davide Cervia; Shuei Sugama; Bruno Conti
Journal:  J Neuroinflammation       Date:  2010-01-29       Impact factor: 8.322

7.  A comprehensive pathway map of IL-18-mediated signalling.

Authors:  D A B Rex; Nupur Agarwal; T S Keshava Prasad; Richard K Kandasamy; Yashwanth Subbannayya; Sneha M Pinto
Journal:  J Cell Commun Signal       Date:  2019-12-20       Impact factor: 5.782

8.  Interlukin-18 Is a Pivot Regulatory Factor on Matrix Metalloproteinase-13 Expression and Brain Astrocytic Migration.

Authors:  Jia-Hong Chen; Chon-Haw Tsai; Hsiao-Yun Lin; Chien-Fang Huang; Yuk-Man Leung; Sheng-Wei Lai; Cheng-Fang Tsai; Pei-Chun Chang; Dah-Yuu Lu; Chingju Lin
Journal:  Mol Neurobiol       Date:  2015-11-12       Impact factor: 5.590

9.  Differences in signaling pathways by IL-1beta and IL-18.

Authors:  Jae-Kwon Lee; Soo-Hyun Kim; Eli C Lewis; Tania Azam; Leonid L Reznikov; Charles A Dinarello
Journal:  Proc Natl Acad Sci U S A       Date:  2004-05-25       Impact factor: 11.205

10.  A single intraperitoneal injection of endotoxin in rats induces long-lasting modifications in behavior and brain protein levels of TNF-α and IL-18.

Authors:  Paola Bossù; Debora Cutuli; Ilaria Palladino; Paola Caporali; Francesco Angelucci; Daniela Laricchiuta; Francesca Gelfo; Paola De Bartolo; Carlo Caltagirone; Laura Petrosini
Journal:  J Neuroinflammation       Date:  2012-05-29       Impact factor: 8.322
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