Literature DB >> 1083743

Immunoradiometric assay of factor VIII related antigen, with observations in 32 patients with von Willebrand's disease.

Z M Ruggeri, P M Mannucci, S L Jeffcoate, G I Ingram.   

Abstract

A solid phase non-competitive immunoradiometric assay (IRMA) has been developed which allows measurement of factor VIII related antigen (VIIIR:AG) levels in normal plasma as low as 2.5 x 10(-4) U/ml. The assay is based on the extraction of VIIIR:AG from test plasma by means of polystrene tubes coated with a specific unlabelled anti-VIIIR:AG rabbit antiserum and subsequent labelling of the extracted antigen with 125I-labelled anti-VIIIR:AG rabbit IgG.

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Year:  1976        PMID: 1083743     DOI: 10.1111/j.1365-2141.1976.tb03533.x

Source DB:  PubMed          Journal:  Br J Haematol        ISSN: 0007-1048            Impact factor:   6.998


  14 in total

1.  Pharmacokinetics and hemostatic effect of different factor VIII/von Willebrand factor concentrates in von Willebrand's disease type III.

Authors:  S Lethagen; E Berntorp; I M Nilsson
Journal:  Ann Hematol       Date:  1992-12       Impact factor: 3.673

2.  Intranasal desmopressin (DDAVP) by spray in mild hemophilia A and von Willebrand's disease type I.

Authors:  S Lethagen; A S Harris; I M Nilsson
Journal:  Blut       Date:  1990-03

3.  Urinary excretion of factor VIII after renal transplantation.

Authors:  Z M Ruggeri; Y B Gordon; N Ardaillou; M J Larrieu; A Tarantino; R Coppola; C Ponticelli; P M Mannucci
Journal:  Br Med J       Date:  1979-02-03

4.  Methods for the detection of haemophilia carriers: a memorandum.

Authors: 
Journal:  Bull World Health Organ       Date:  1977       Impact factor: 9.408

5.  [Method of detecting the transmission of hemophilia: report of the WHO].

Authors: 
Journal:  Bull World Health Organ       Date:  1979       Impact factor: 9.408

6.  The von Willebrand-syndrome.

Authors:  I Scharrer
Journal:  Blut       Date:  1983-09

7.  Combined functional and immunochemical analysis of normal and abnormal human factor X.

Authors:  D S Fair; E F Plow; T S Edgington
Journal:  J Clin Invest       Date:  1979-10       Impact factor: 14.808

8.  von Willebrand factor interaction with the glycoprotein IIb/IIa complex. Its role in platelet function as demonstrated in patients with congenital afibrinogenemia.

Authors:  L De Marco; A Girolami; T S Zimmerman; Z M Ruggeri
Journal:  J Clin Invest       Date:  1986-04       Impact factor: 14.808

9.  Studies on hemophilia A in Sardinia bearing on the problems of multiple allelism, carrier detection, and differential mutation rate in the two sexes.

Authors:  G Filippi; P M Mannucci; R Coppola; A Farris; A Rinaldi; M Siniscalco
Journal:  Am J Hum Genet       Date:  1984-01       Impact factor: 11.025

Review 10.  Haemophilia: strategies for carrier detection and prenatal diagnosis.

Authors:  I R Peake; D P Lillicrap; V Boulyjenkov; E Briet; V Chan; E K Ginter; E M Kraus; R Ljung; P M Mannucci; K Nicolaides
Journal:  Bull World Health Organ       Date:  1993       Impact factor: 9.408

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