Literature DB >> 10836068

Convergent C-glycolipid synthesis via the Ramberg-Bäcklund reaction: active antiproliferative glycolipids.

G Yang1, R W Franck, H S Byun, R Bittman, P Samadder, G Arthur.   

Abstract

[formula: see text] A novel methodology has been developed, employing the Ramberg-Bäcklund rearrangement and ionic hydrogenation to synthesize C-glycosides with high stereoselectivity at the anomeric center. The C-glycolipid 14b exhibits antiproliferative properties similar to those of O-glycoside analogue 14a.

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Year:  1999        PMID： 10836068     DOI： 10.1021/ol991211f

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  4 in total

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Journal:  C R Chim       Date:  2012-01-01       Impact factor: 3.117

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Journal:  Lipids       Date:  2015-04-18       Impact factor: 1.880

Review 3.  The Potential of Novel Lipid Agents for the Treatment of Chemotherapy-Resistant Human Epithelial Ovarian Cancer.

Authors:  Mark W Nachtigal; Alon D Altman; Rajat Arora; Frank Schweizer; Gilbert Arthur
Journal:  Cancers (Basel)       Date:  2022-07-07       Impact factor: 6.575

4.  Superior protection against malaria and melanoma metastases by a C-glycoside analogue of the natural killer T cell ligand alpha-Galactosylceramide.

Authors:  John Schmieg; Guangli Yang; Richard W Franck; Moriya Tsuji
Journal:  J Exp Med       Date:  2003-12-01       Impact factor: 14.307
  4 in total

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