Literature DB >> 10836036

Synthesis of trisubstituted alkenes via olefin cross-metathesis.

A K Chatterjee1, R H Grubbs.   

Abstract

[formula: see text] Trisubstituted alkenes have been prepared for the first time via intermolecular olefin cross-metathesis, using 1,3-dimesityl-4,5-dihydroimidazol-2-ylidene ruthenium alkylidene complexes 3a,b in good yields with moderate E selectivity. In addition, protected alcohols near the geminal disubstituted olefin improve reactivity for cross-metathesis.

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Year:  1999        PMID： 10836036     DOI： 10.1021/ol991023p

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  16 in total

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2.  Toward an enantioselective synthesis of (-)-zampanolide: preparation of the C9-C20 region.

Authors:  Matthew R Wilson; Richard E Taylor
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3.  Low catalyst loadings in olefin metathesis: synthesis of nitrogen heterocycles by ring-closing metathesis.

Authors:  Kevin M Kuhn; Timothy M Champagne; Soon Hyeok Hong; Wen-Hao Wei; Andrew Nickel; Choon Woo Lee; Scott C Virgil; Robert H Grubbs; Richard L Pederson
Journal:  Org Lett       Date:  2010-03-05       Impact factor: 6.005

4.  Ruthenium Vinyl Carbene Intermediates in Enyne Metathesis.

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Journal:  Coord Chem Rev       Date:  2007-03-01       Impact factor: 22.315

5.  Iridium-catalyzed, regio- and enantioselective allylic substitution with aromatic and aliphatic sulfinates.

Authors:  Mitsuhiro Ueda; John F Hartwig
Journal:  Org Lett       Date:  2010-01-01       Impact factor: 6.005

6.  Facile Pd(II)- and Ni(II)-catalyzed isomerization of terminal alkenes into 2-alkenes.

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Journal:  J Org Chem       Date:  2009-06-19       Impact factor: 4.354

7.  Synthesis of stable and potent delta/mu opioid peptides: analogues of H-Tyr-c[D-Cys-Gly-Phe-D-Cys]-OH by ring-closing metathesis.

Authors:  Adriano Mollica; Giovanni Guardiani; Peg Davis; Shou-Wu Ma; Frank Porreca; Josephine Lai; Luisa Mannina; Anatoli P Sobolev; Victor J Hruby
Journal:  J Med Chem       Date:  2007-06-01       Impact factor: 7.446

8.  Abnormal Beckmann fragmentation/ring closing metathesis route for preparation of 18-nor-Delta-androgens and their 18-nor-13,17-epoxide derivatives.

Authors:  Cunde Wang; Nigam P Rath; Douglas F Covey
Journal:  Tetrahedron Lett       Date:  2006-11-06       Impact factor: 2.415

9.  One-pot synthesis of trisubstituted conjugated dienes via sequential Suzuki-Miyaura cross-coupling with alkenyl- and alkyltrifluoroborates.

Authors:  Gary A Molander; Yasuo Yokoyama
Journal:  J Org Chem       Date:  2006-03-17       Impact factor: 4.354

10.  Total synthesis of (+/-)-halichlorine, (+/-)-pinnaic acid, and (+/-)-tauropinnaic acid.

Authors:  Hamish S Christie; Clayton H Heathcock
Journal:  Proc Natl Acad Sci U S A       Date:  2004-08-06       Impact factor: 11.205
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