Literature DB >> 10836033

Epicalyxin F and calyxin I: two novel antiproliferative diarylheptanoids from the seeds of Alpinia blepharocalyx.

M B Gewali1, Y Tezuka, A H Banskota, M S Ali, I Saiki, H Dong, S Kadota.   

Abstract

[formula: see text] Epicalyxin F (1) and calyxin I (2), two novel diarylheptanoids, were isolated from a residual fraction of an EtOH extract of Alpinia blepharocalyx. Calyxin I (2) represented a new carbon skeleton, and epicalyxin F (1) possessed potent antiproliferative activity toward HT-1080 fibrosarcoma and colon 26-L5 carcinoma with ED50 values of 1.71 and 0.89 microM, respectively.

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Year:  1999        PMID: 10836033     DOI: 10.1021/ol990260p

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  5 in total

1.  Synthesis and structural reassignment of (+)-epicalyxin F.

Authors:  Xia Tian; Scott D Rychnovsky
Journal:  Org Lett       Date:  2007-10-25       Impact factor: 6.005

2.  Evidence for pi-stacking as a source of stereocontrol in the synthesis of the core pyranochromene ring system common to calyxin I, calyxin J, and epicalyxin J.

Authors:  Sidika Polat Cakir; Sean Stokes; Andrzej Sygula; Keith T Mead
Journal:  J Org Chem       Date:  2009-10-02       Impact factor: 4.354

3.  Helichrysetin and TNF‑α synergistically promote apoptosis by inhibiting overactivation of the NF‑κB and EGFR signaling pathways in HeLa and T98G cells.

Authors:  Zhiying Wang; Xiaohui Liang; Aizhen Xiong; Lili Ding; Wei Li; Li Yang; Xiaojun Wu; Hailian Shi; Yue Zhou; Zhengtao Wang
Journal:  Int J Mol Med       Date:  2021-02-12       Impact factor: 4.101

4.  Induction of apoptosis and cell cycle blockade by helichrysetin in a549 human lung adenocarcinoma cells.

Authors:  Yen Fong Ho; Saiful Anuar Karsani; Wai Kuan Yong; Sri Nurestri Abd Malek
Journal:  Evid Based Complement Alternat Med       Date:  2013-03-03       Impact factor: 2.629

Review 5.  Diarylheptanoids as nutraceutical: A review.

Authors:  G Ganapathy; R Preethi; J A Moses; C Anandharamakrishnan
Journal:  Biocatal Agric Biotechnol       Date:  2019-03-26
  5 in total

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