Literature DB >> 1083558

Mitogenic properties of polyene antibiotics for murine B cells.

L Hammarström, E Smith.   

Abstract

Two polyene antibiotics, nystatin and amphotericin B, were found to be mitogenic for mouse spleen cells as measured by induction of DNA synthesis and polyclonal antibody production. This effect was demonstrated on spleen cells from nude mice and anti-theta-treated spleen cells from normal mice. No effect was found on cortisone-resistant thymocytes or on spleen cells treated with anti-mouse bone marrow-derived lymphocyte antigen antiserum. Nor was there any effect on spleen cells passed through a nylon fiber column. Thus we conclude that nystatin and amphotericin B are murine B-cell mitogens.

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Year:  1976        PMID： 1083558     DOI： 10.1111/j.1365-3083.1976.tb02990.x

Source DB:  PubMed          Journal:  Scand J Immunol        ISSN： 0300-9475            Impact factor:   3.487


  5 in total

1.  Effect of liposomal amphotericin B on murine macrophages and lymphocytes.

Authors:  R T Mehta; K Mehta; G Lopez-Berestein; R L Juliano
Journal:  Infect Immun       Date:  1985-02       Impact factor: 3.441

2.  Stimulatory, permeabilizing, and toxic effects of amphotericin B on L cells.

Authors:  J Brajtburg; S Elberg; J Medoff; G S Kobayashi; D Schlessinger; G Medoff
Journal:  Antimicrob Agents Chemother       Date:  1984-12       Impact factor: 5.191

3.  Inhibition of proliferation of a murine myeloma cell line and mitogen-stimulated B lymphocytes by the antibiotic amphotericin B (Fungizone).

Authors:  E V Walls; J E Kay
Journal:  Immunology       Date:  1982-09       Impact factor: 7.397

Review 4.  Membrane effects of the polyene antibiotic amphotericin B and of some of its derivatives on lymphocytes.

Authors:  N Henry-Toulmé; P Sarthou; M Seman; J Bolard
Journal:  Mol Cell Biochem       Date:  1989 Nov 23-Dec 19       Impact factor: 3.396

Review 5.  Lipid rafts in T cell signalling and disease.

Authors:  Elizabeth C Jury; Fabian Flores-Borja; Panagiotis S Kabouridis
Journal:  Semin Cell Dev Biol       Date:  2007-08-19       Impact factor: 7.727
  5 in total

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