Literature DB >> 10835416

A glucose transporter chimera confers a dominant negative glucose starvation phenotype in Saccharomyces cerevisiae.

P W Sherwood1, I Katic, P Sanz, M Carlson.   

Abstract

A family of glucose transporters mediates glucose uptake in Saccharomyces cerevisiae. We show that the dominant mutation GSF4-1, which impairs glucose repression of SUC2, results in a nonfunctional chimera of the transporters Hxt1p and Hxt4p. Hxt1/4p inhibits the function of wild-type glucose transporters. Similar mutations may facilitate analysis of the major facilitator superfamily.

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Year:  2000        PMID： 10835416      PMCID： PMC1461109     

Source DB:  PubMed          Journal:  Genetics        ISSN： 0016-6731            Impact factor:   4.562


  22 in total

Review 1.  The hexose transporter family of Saccharomyces cerevisiae.

Authors:  A L Kruckeberg
Journal:  Arch Microbiol       Date:  1996-11       Impact factor: 2.552

Review 2.  The molecular genetics of hexose transport in yeasts.

Authors:  E Boles; C P Hollenberg
Journal:  FEMS Microbiol Rev       Date:  1997-08       Impact factor: 16.408

3.  Kinetic characterization of individual hexose transporters of Saccharomyces cerevisiae and their relation to the triggering mechanisms of glucose repression.

Authors:  E Reifenberger; E Boles; M Ciriacy
Journal:  Eur J Biochem       Date:  1997-04-15

4.  A novel signal transduction pathway in Saccharomyces cerevisiae defined by Snf3-regulated expression of HXT6.

Authors:  H Liang; R F Gaber
Journal:  Mol Biol Cell       Date:  1996-12       Impact factor: 4.138

5.  Mutations in GSF1 and GSF2 alter glucose signaling in Saccharomyces cerevisiae.

Authors:  P W Sherwood; M Carlson
Journal:  Genetics       Date:  1997-10       Impact factor: 4.562

Review 6.  Yeast sugar transporters.

Authors:  L F Bisson; D M Coons; A L Kruckeberg; D A Lewis
Journal:  Crit Rev Biochem Mol Biol       Date:  1993       Impact factor: 8.250

Review 7.  A major superfamily of transmembrane facilitators that catalyse uniport, symport and antiport.

Authors:  M D Marger; M H Saier
Journal:  Trends Biochem Sci       Date:  1993-01       Impact factor: 13.807

8.  The GLC7 type 1 protein phosphatase is required for glucose repression in Saccharomyces cerevisiae.

Authors:  J Tu; M Carlson
Journal:  Mol Cell Biol       Date:  1994-10       Impact factor: 4.272

9.  Glucose transporter function is controlled by transporter oligomeric structure. A single, intramolecular disulfide promotes GLUT1 tetramerization.

Authors:  R J Zottola; E K Cloherty; P E Coderre; A Hansen; D N Hebert; A Carruthers
Journal:  Biochemistry       Date:  1995-08-01       Impact factor: 3.162

10.  Three different regulatory mechanisms enable yeast hexose transporter (HXT) genes to be induced by different levels of glucose.

Authors:  S Ozcan; M Johnston
Journal:  Mol Cell Biol       Date:  1995-03       Impact factor: 4.272
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  3 in total

1.  Protein-protein interactions between sucrose transporters of different affinities colocalized in the same enucleate sieve element.

Authors:  Anke Reinders; Waltraud Schulze; Christina Kühn; Laurence Barker; Alexander Schulz; John M Ward; Wolf B Frommer
Journal:  Plant Cell       Date:  2002-07       Impact factor: 11.277

2.  Altering sphingolipid metabolism in Saccharomyces cerevisiae cells lacking the amphiphysin ortholog Rvs161 reinitiates sugar transporter endocytosis.

Authors:  Jeanelle Morgan; Paula McCourt; Lauren Rankin; Evelyn Swain; Lyndi M Rice; Joseph T Nickels
Journal:  Eukaryot Cell       Date:  2009-03-13

3.  Interactions between co-expressed Arabidopsis sucrose transporters in the split-ubiquitin system.

Authors:  Waltraud X Schulze; Anke Reinders; John Ward; Sylvie Lalonde; Wolf B Frommer
Journal:  BMC Biochem       Date:  2003-03-18       Impact factor: 4.059
  3 in total

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