Literature DB >> 10833561

Lumbar catheterization of the subarachnoid space with a 32-gauge polyurethane catheter in the rat.

E M Pogatzki1, P K Zahn, T J Brennan.   

Abstract

Chronic catheterization of the subarachnoid space of rats is an important tool for intrathecal drug delivery in pharmacologic investigations of pain. We describe a technique using direct lumbar insertion of a small 32-gauge polyurethane (PU) catheter without extensive surgery. Location of the catheter was confirmed with 2% lidocaine injection 1 day later, and methylene blue injection after 7-14 days. This method improved recovery of the rat after catheter implantation and reduced neurologic complications. Copyright 2000 European Federation of Chapters of the International Association for the Study of Pain.

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Year:  2000        PMID： 10833561     DOI： 10.1053/eujp.1999.0157

Source DB:  PubMed          Journal:  Eur J Pain        ISSN： 1090-3801            Impact factor:   3.931


  30 in total

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Authors:  J J Maire; L N Close; M M Heinricher; N R Selden
Journal:  Eur J Pain       Date:  2015-04-05       Impact factor: 3.931

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7.  Ketoprofen produces modality-specific inhibition of pain behaviors in rats after plantar incision.

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8.  Intrathecal neuropeptide Y reduces behavioral and molecular markers of inflammatory or neuropathic pain.

Authors:  A B Intondi; M N Dahlgren; M A Eilers; B K Taylor
Journal:  Pain       Date:  2007-10-31       Impact factor: 6.961

9.  Blockade of NMDA receptors prevents analgesic tolerance to repeated transcutaneous electrical nerve stimulation (TENS) in rats.

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10.  The roles of nerve growth factor and cholecystokinin in the enhancement of morphine analgesia in a rodent model of central nervous system inflammation.

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