Literature DB >> 10832946

Quinolones and tendon ruptures.

J M Casparian1, M Luchi, R E Moffat, D Hinthorn.   

Abstract

We report two cases of tendon rupture associated with ciprofloxacin. One patient had a complete rupture of an Achilles tendon 6 months after taking the medication. The other case involved a partial rupture of the subscapularis tendon. Both ruptures occurred with minimal mechanical stress on the tendons, suggesting that the fluoroquinolone increased the susceptibility to rupture. We also review the literature describing the association between fluoroquinolones and tendon rupture and discuss the mechanisms explaining the heightened risk of tendon rupture associated with these drugs.

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Year:  2000        PMID: 10832946

Source DB:  PubMed          Journal:  South Med J        ISSN: 0038-4348            Impact factor:   0.954


  14 in total

Review 1.  Achilles tendinopathy: some aspects of basic science and clinical management.

Authors:  D Kader; A Saxena; T Movin; N Maffulli
Journal:  Br J Sports Med       Date:  2002-08       Impact factor: 13.800

2.  The Risk of Fluoroquinolone-induced Tendinopathy and Tendon Rupture: What Does The Clinician Need To Know?

Authors:  Grace K Kim
Journal:  J Clin Aesthet Dermatol       Date:  2010-04

3.  Spontaneous rupture of multiple extensor tendons following repeated steroid injections: a case report.

Authors:  Bing Zhang; Sheng-ting Hu; Ying-ze Zhang
Journal:  Orthop Surg       Date:  2012-05       Impact factor: 2.071

Review 4.  Fluoroquinolones and tendinopathy: a guide for athletes and sports clinicians and a systematic review of the literature.

Authors:  Trevor Lewis; Jill Cook
Journal:  J Athl Train       Date:  2014-04-24       Impact factor: 2.860

5.  A rare case of ciprofloxacin-induced bilateral rupture of the Achilles tendon.

Authors:  Trevor G Lewis
Journal:  BMJ Case Rep       Date:  2009-03-05

6.  Bilateral spontaneous non-traumatic rupture of the Achilles tendon: a case report.

Authors:  Zubair Khanzada; Ulfin Rethnam; David Widdowson; Ahmed Mirza
Journal:  J Med Case Rep       Date:  2011-06-30

7.  Efficacy and safety of levofloxacin in the context of other contemporary fluoroquinolones: a review.

Authors:  Peter Ball
Journal:  Curr Ther Res Clin Exp       Date:  2003-11

8.  Spontaneous bilateral Achilles tendon rupture in a patient treated with oral levofloxacin.

Authors:  A E Salvi; G P Metelli; A Bosco; A Berizzi; S A Hacking; A Cantalamessa
Journal:  J Orthop Traumatol       Date:  2007-06-08

9.  Levofloxacin, tendon rupture and acute kidney injury: Thinking outside the box.

Authors:  S Senthilkumaran; S Shah; N Balamurugan; P Thirumalaikolundusubramanian
Journal:  Indian J Nephrol       Date:  2012-01

10.  Oxidative stress induced by fluoroquinolones on treatment for complicated urinary tract infections in Indian patients.

Authors:  V Talla; Pr Veerareddy
Journal:  J Young Pharm       Date:  2011-10
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