Literature DB >> 10832468

Polio eradication--target 2000.

S Gomber1, K N Agarwal.   

Abstract

Poliovirus an enterovirus is of 3 types (1, 2 & 3). The 1 poliovirus is most often the cause of paralysis. Poliomyelitis can be eradicated from human soil as man is the only reservoir of this infection and effective vaccines are also available for its control. Inactivated poliovirus vaccine (IPV) confers mainly the humoral immunity in comparison to oral polio vaccine (OPV) which gives the intestinal immunity as well. OPV has been recommended by the WHO as the vaccine of choice for global eradication of polio because of its superior ability to inhibit spread of wild polio virus, low cost and its ease of administration. 70-90% of polio cases occur in children less than 3 year of age. Each paralytic case which is the tip of an iceberg probably represents 100 to 1,000 infected persons in the community. The incidence of poliomyelitis is on the decline with 145 of 213 countries today report 0 case of polio. Central Africa & South Asia are the principal reservoirs of wild poliovirus with nearly two thirds of cases being reported from Indian subcontinent. Components of eradication strategy are: sustained high levels of immunisation, annual mass vaccination campaigns of OPV to all children under 5 years of age, establishment of extremely sensitive surveillance systems and targeted immunisation to areas and populations where poliovirus transmission is likely to persist. The task of global eradication of poliomyelitis is uphill but well within our reach. A strong will and political commitment by the Government of India is leading the nation to the goal of polio-free world by the year 2,000.

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Year:  1996        PMID: 10832468     DOI: 10.1007/bf02905722

Source DB:  PubMed          Journal:  Indian J Pediatr        ISSN: 0019-5456            Impact factor:   1.967


  18 in total

1.  Expanded programme on immunization. Poliomyelitis outbreak.

Authors: 
Journal:  Wkly Epidemiol Rec       Date:  1992-11-06

2.  Outbreak of paralytic poliomyelitis in Oman: evidence for widespread transmission among fully vaccinated children.

Authors:  R W Sutter; P A Patriarca; S Brogan; P G Malankar; M A Pallansch; O M Kew; A G Bass; S L Cochi; J P Alexander; D B Hall
Journal:  Lancet       Date:  1991-09-21       Impact factor: 79.321

3.  Expanded programme on immunization. Poliomyelitis outbreak, 1992.

Authors: 
Journal:  Wkly Epidemiol Rec       Date:  1993-10-08

Review 4.  Epidemiology of poliomyelitis in the United States one decade after the last reported case of indigenous wild virus-associated disease.

Authors:  P M Strebel; R W Sutter; S L Cochi; R J Biellik; E W Brink; O M Kew; M A Pallansch; W A Orenstein; A R Hinman
Journal:  Clin Infect Dis       Date:  1992-02       Impact factor: 9.079

5.  Poliomyelitis in vaccinated children.

Authors:  S Sen; D Sharma; S Singh; P Malik; S Khare; S Kumari
Journal:  Indian Pediatr       Date:  1989-05       Impact factor: 1.411

6.  An outbreak of poliomyelitis in Andhra Pradesh (South India).

Authors:  N Murthy; P Bhaskaram; M V Murali; M Sukanya; C R Rao
Journal:  Indian Pediatr       Date:  1994-05       Impact factor: 1.411

7.  Risk of vaccine-associated paralytic poliomyelitis in Latin America, 1989-91.

Authors:  J K Andrus; P M Strebel; C A de Quadros; J M Olivé
Journal:  Bull World Health Organ       Date:  1995       Impact factor: 9.408

8.  Strategies for elimination of poliomyelitis in different parts of the world with use of oral poliovirus vaccine.

Authors:  A B Sabin
Journal:  Rev Infect Dis       Date:  1984 May-Jun

9.  Cuba: mass polio vaccination program, 1962-1982.

Authors:  R Rodríguez Cruz
Journal:  Rev Infect Dis       Date:  1984 May-Jun

10.  Paralytic poliomyelitis: seasoned strategies, disappearing disease.

Authors:  H F Hull; N A Ward; B P Hull; J B Milstien; C de Quadros
Journal:  Lancet       Date:  1994-05-28       Impact factor: 79.321

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