Literature DB >> 10832230

Plumbism--a mimicker of common childhood symptoms.

V Kalra1, S Gulati, K T Chitralekha, P Pande, S D Makhijani, C S Sharma.   

Abstract

Lead poisoning is a preventable entity that can affect almost every system of the body. Its toxic effects range from subtle common childhood symptoms to even death. In a prospective study forty six children with at least one symptom compatible with plumbism were enrolled after screening patients attending medical services at AIIMS. The work-up included a detailed clinical history and examination including intelligence quotient (IQ) and behaviour. Blood lead levels were estimated in all with due precautions. Their ages ranged from 2.5 to 18 years and M:F ratio was 2:1. The common symptoms included unexplained recurrent colic (39), anorexia (21), sporadic vomiting and constipation (13), pigmented gum lines (11), growth failure (11), history of pica (9) etc. None of the children had acceptable blood lead levels (< 10 micrograms/dl). Ninety three per cent children had levels > 20 micrograms/dl and 47.8% had > 45 micrograms/dl. Statistically significant correlation with blood lead levels was seen with most symptoms. Plumbism can mimic common childhood illnesses and should be investigated in children with a clinically compatible profile. Community awareness with regard to pica reduction may be an important preventive measure. This silent epidemic needs to be aggressively tackled by a multipronged approach.

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Year:  2000        PMID: 10832230     DOI: 10.1007/bf02726170

Source DB:  PubMed          Journal:  Indian J Pediatr        ISSN: 0019-5456            Impact factor:   1.967


  23 in total

1.  Blood lead levels in urban and rural Indian children.

Authors:  R K Kumar; N Kesaree
Journal:  Indian Pediatr       Date:  1999-03       Impact factor: 1.411

Review 2.  Heavy metal toxicity, part II: lead and metal fume fever.

Authors:  K A Graeme; C V Pollack
Journal:  J Emerg Med       Date:  1998 Mar-Apr       Impact factor: 1.484

3.  Acute lead encephalopathy in early infancy--clinical presentation and outcome.

Authors:  A al Khayat; N S Menon; M R Alidina
Journal:  Ann Trop Paediatr       Date:  1997-03

Review 4.  Toxicity of lead at low dose.

Authors:  P J Landrigan
Journal:  Br J Ind Med       Date:  1989-09

5.  Hazard from lead to children in Delhi.

Authors:  S Sinclair; S K Mittal; N Basu; O P Ghai; N K Bhide
Journal:  Indian Pediatr       Date:  1973-01       Impact factor: 1.411

6.  Classification and categorization in child psychiatry.

Authors:  M Rutter
Journal:  J Child Psychol Psychiatry       Date:  1965-11       Impact factor: 8.982

7.  Kinetics of lead interaction with human erythrocytes.

Authors:  D Barltrop; A M Smith
Journal:  Postgrad Med J       Date:  1975-11       Impact factor: 2.401

Review 8.  Lead poisoning.

Authors:  P J Landrigan; A C Todd
Journal:  West J Med       Date:  1994-08

9.  A rapid electrothermal atomic absorption spectrophotometric method for cadmium and lead in human whole blood.

Authors:  K S Subramanian; J C Meranger
Journal:  Clin Chem       Date:  1981-11       Impact factor: 8.327

10.  Blood lead, hearing thresholds, and neurobehavioral development in children and youth.

Authors:  J Schwartz; D Otto
Journal:  Arch Environ Health       Date:  1987 May-Jun
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  1 in total

Review 1.  A Comparative Analysis of Heavy Metal Effects on Medicinal Plants.

Authors:  Susmita Mukherjee; Nivedita Chatterjee; Asmeeta Sircar; Shimantika Maikap; Abhilasha Singh; Sudeshna Acharyya; Sonali Paul
Journal:  Appl Biochem Biotechnol       Date:  2022-04-30       Impact factor: 2.926

  1 in total

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