Literature DB >> 10832225

Granulocyte macrophage-colony stimulating factor (GM-CSF) in neonatal neutropenia.

M Ray1, K Mukhopadhyay, A Narang.   

Abstract

Neutropenia in neonates is often associated with sepsis, prematurity and maternal hypertension with increased risk of mortality. We describe two neonates with neutropenia treated with granulocyte macrophage colony stimulating factor. The total and absolute neutrophil counts showed a marked response and led to a favourable outcome. Human granulocyte macrophage colony stimulating factor may be used as an adjuvant therapy for neonatal neutropenia of different aetiologies.

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Year:  2000        PMID： 10832225     DOI： 10.1007/bf02802647

Source DB:  PubMed          Journal:  Indian J Pediatr        ISSN： 0019-5456            Impact factor:   1.967


  11 in total

Review 1.  Cytokines: a new immunotherapy.

Authors:  M S Cairo
Journal:  Clin Perinatol       Date:  1991-06       Impact factor: 3.430

Review 2.  Granulocyte and granulocyte-macrophage colony-stimulating factors.

Authors:  W P Steward
Journal:  Lancet       Date:  1993-07-17       Impact factor: 79.321

3.  Role of circulating complement and polymorphonuclear leukocyte transfusion in treatment and outcome in critically ill neonates with sepsis.

Authors:  M S Cairo; C Worcester; R Rucker; G A Bennetts; R Amlie; R Perkin; N Anas; D Hicks
Journal:  J Pediatr       Date:  1987-06       Impact factor: 4.406

4.  Prophylactic or simultaneous administration of recombinant human granulocyte colony stimulating factor in the treatment of group B streptococcal sepsis in neonatal rats.

Authors:  M S Cairo; D Mauss; S Kommareddy; K Norris; C van de Ven; H Modanlou
Journal:  Pediatr Res       Date:  1990-06       Impact factor: 3.756

5.  Neutropenia in an extremely premature infant treated with recombinant human granulocyte colony-stimulating factor.

Authors:  R L Roberts; C M Szelc; S M Scates; M T Boyd; K M Soderstrom; M W Davis; J A Glaspy
Journal:  Am J Dis Child       Date:  1991-07

6.  Incidence, neutrophil kinetics, and natural history of neonatal neutropenia associated with maternal hypertension.

Authors:  J M Koenig; R D Christensen
Journal:  N Engl J Med       Date:  1989-08-31       Impact factor: 91.245

Review 7.  Potential role of colony-stimulating factors in the prevention and treatment of infectious diseases.

Authors:  D C Dale
Journal:  Clin Infect Dis       Date:  1994-02       Impact factor: 9.079

8.  A randomized, placebo-controlled trial of recombinant human granulocyte colony-stimulating factor administration in newborn infants with presumed sepsis: significant induction of peripheral and bone marrow neutrophilia.

Authors:  E R Gillan; R D Christensen; Y Suen; R Ellis; C van de Ven; M S Cairo
Journal:  Blood       Date:  1994-09-01       Impact factor: 22.113

9.  Phase I/II study of recombinant human granulocyte colony-stimulating factor in patients receiving intensive chemotherapy for small cell lung cancer.

Authors:  M H Bronchud; J H Scarffe; N Thatcher; D Crowther; L M Souza; N K Alton; N G Testa; T M Dexter
Journal:  Br J Cancer       Date:  1987-12       Impact factor: 7.640

10.  Recombinant human granulocyte colony-stimulating factor. Effects on hematopoiesis in normal and cyclophosphamide-treated primates.

Authors:  K Welte; M A Bonilla; A P Gillio; T C Boone; G K Potter; J L Gabrilove; M A Moore; R J O'Reilly; L M Souza
Journal:  J Exp Med       Date:  1987-04-01       Impact factor: 14.307
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