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Literature DB >> 10829946

Paradoxical response to antitubercular drugs.

S Kumar¹, V Puri, M M Mehndiratta, S Gupta, A Bhutani, C Sharma.

Abstract

Seven patients with paradoxical response to antitubercular drugs are reported. In three cases of intracranial tuberculomas, newer lesions appeared and in two cases preexisting tuberculomas enlarged. In two cases of tubercular meningitis, multiple tuberculomas appeared. All these cases exhibited newer symptoms and CT/MBI revealed the paradoxical response to antitubercular drugs. All responded to continued conservative therapy, with addition of pyrazinamide.

Entities: Chemical Disease Species

Mesh：

Substances：
Antitubercular Agents

Year: 1995 PMID： 10829946 DOI： 10.1007/bf02825120

Source DB: PubMed Journal: Indian J Pediatr ISSN： 0019-5456 Impact factor: 1.967

19 in total

1. Transient appearance of intracranial tuberculoma during treatment of tuberculous meningitis.

Authors: W E Shepard; M L Field; D H James; I L Tonkin
Journal: Pediatr Infect Dis Date: 1986 Sep-Oct

2. Symptomatic intracranial tuberculoma developing during treatment of tuberculosis: a report of 10 patients and review of the literature.

Authors: R Teoh; M J Humphries; G O'Mahony
Journal: Q J Med Date: 1987-05

Paradoxical response to antitubercular drugs.

1. Transient appearance of intracranial tuberculoma during treatment of tuberculous meningitis.

2. Symptomatic intracranial tuberculoma developing during treatment of tuberculosis: a report of 10 patients and review of the literature.

3. Sequential computerized axial tomography in tuberculous meningitis.

4. Cerebral tuberculomas developing during treatment of tuberculous meningitis.

5. Compliance of patients and physicians: experience and lessons from tuberculosis-II.

6. Tuberculous brain abscess. Report of a case and review of the literature.

7. Intracranial tuberculomas: correlation of computerized tomography with clinico-pathological findings.

8. Paradoxical response of intracranial tuberculomas during chemotherapy: an immunologic phenomenon?

9. Appearance of tuberculoma during the course of TB meningitis.

10. Intracranial tuberculoma and hydrocephalus developing during treatment of tuberculous meningitis.

1. Serial study of clinical and CT changes in tuberculous meningitis.

2. Use of IMiD3, a thalidomide analog, as an adjunct to therapy for experimental tuberculous meningitis.