Literature DB >> 10828797

Multinodular goiter: the surgical procedure of choice.

R Cohen-Kerem1, P Schachter, M Sheinfeld, E Baron, O Cohen.   

Abstract

Surgical management of multinodular goiter (MNG) poses an ongoing dilemma between radical resection with its associated complications and partial resection, which carries the risk of recurrence and increased morbidity and difficulty for rethyroidectomy. This study was designed to evaluate the recurrence rate and need for reoperation in a carefully selected population of MNG patients, after nontotal thyroidectomy. The study addressed a highly selected population of patients who were treated and thoroughly evaluated at one surgical department for several years. We analyzed the recurrence rate of MNG in 124 patients. The follow-up duration extended from 6 to 516 months (mean 93 months). The general recurrence rate for all nontotal bilateral thyroidectomies was 21% (21/100 patients), increasing from 13.4% to 60% according to the extent of resection. The average time for recurrence was 105 months (8.75 years). Among the patients with recurrent MNG, only 4 (4% of the patients with nontotal bilateral thyroidectomy) required secondary surgical interventions with no resultant morbidity. In our series of very highly selected patients, the recurrence rate for nontotal thyroidectomy was high (21%); however, the need for secondary surgical intervention was low (4%). Thus nontotal thyroidectomy for MNG is legitimate. However, we suggest that the surgical procedure of choice be tailored according to the severity of the disease and the patient's general condition.

Entities:  

Mesh:

Year:  2000        PMID: 10828797     DOI: 10.1016/S0194-59980070012-X

Source DB:  PubMed          Journal:  Otolaryngol Head Neck Surg        ISSN: 0194-5998            Impact factor:   5.591


  7 in total

Review 1.  Less than total thyroidectomy for goiter: when and how?

Authors:  Özer Makay
Journal:  Gland Surg       Date:  2017-12

2.  Surgery for recurrent goiter: complication rate and role of the thyroid-stimulating hormone-suppressive therapy after the first operation.

Authors:  P Miccoli; G Frustaci; A Fosso; M Miccoli; G Materazzi
Journal:  Langenbecks Arch Surg       Date:  2014-11-29       Impact factor: 3.445

Review 3.  Is total thyroidectomy the surgical procedure of choice for benign multinodular goiter? An evidence-based review.

Authors:  Gaurav Agarwal; Vivek Aggarwal
Journal:  World J Surg       Date:  2008-07       Impact factor: 3.352

Review 4.  Treatment and prevention of recurrence of multinodular goiter: an evidence-based review of the literature.

Authors:  Jacob Moalem; Insoo Suh; Quan-Yang Duh
Journal:  World J Surg       Date:  2008-07       Impact factor: 3.352

5.  Prospective study of postoperative complications after total thyroidectomy for multinodular goiters by surgeons with experience in endocrine surgery.

Authors:  Antonio Ríos Zambudio; José Rodríguez; Juan Riquelme; Teresa Soria; Manuel Canteras; Pascual Parrilla
Journal:  Ann Surg       Date:  2004-07       Impact factor: 12.969

6.  Prospective analysis of risk for hypothyroidism after hemithyroidectomy.

Authors:  Virgilijus Beisa; Darius Kazanavicius; Arminas Skrebunas; Gintaras Simutis; Justinas Ivaska; Kestutis Strupas
Journal:  Int J Endocrinol       Date:  2015-03-30       Impact factor: 3.257

7.  Patient outcomes following surgical management of multinodular goiter: Does multinodularity increase the risk of thyroid malignancy?

Authors:  Yann-Sheng Lin; Hsin-Yi Wu; Ming-Chin Yu; Chih-Chieh Hsu; Tzu-Chieh Chao
Journal:  Medicine (Baltimore)       Date:  2016-07       Impact factor: 1.889

  7 in total

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