Literature DB >> 10828600

The eosinophil peroxidase gene forms a cluster with the genes for myeloperoxidase and lactoperoxidase on human chromosome 17.

K Sakamaki1, N Kanda, T Ueda, E Aikawa, S Nagata.   

Abstract

Eosinophil peroxidase (EPX) is one of a family of mammalian peroxidases that includes myeloperoxidase (MPO), lactoperoxidase (LPO), and thyroid peroxidase (TPO). Here we show that the human EPX gene maps to chromosome 17q23.1, which localizes 34 kb from the LPO and MPO genes. Our results demonstrate that the EPX, LPO, and MPO genes form a cluster on human chromosome 17. Copyright 2000 S. Karger AG, Basel

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Year:  2000        PMID： 10828600     DOI： 10.1159/000015529

Source DB:  PubMed          Journal:  Cytogenet Cell Genet        ISSN： 0301-0171


  3 in total

1.  Neutrophils employ the myeloperoxidase system to generate antimicrobial brominating and chlorinating oxidants during sepsis.

Authors:  J P Gaut; G C Yeh; H D Tran; J Byun; J P Henderson; G M Richter; M L Brennan; A J Lusis; A Belaaouaj; R S Hotchkiss; J W Heinecke
Journal:  Proc Natl Acad Sci U S A       Date:  2001-10-02       Impact factor: 11.205

2.  Terminally Differentiating Eosinophils Express Neutrophil Primary Granule Proteins as well as Eosinophil-specific Granule Proteins in a Temporal Manner.

Authors:  Karam Kim; Sae Mi Hwang; Sung Min Kim; Sung Woo Park; Yunjae Jung; Il Yup Chung
Journal:  Immune Netw       Date:  2017-12-13       Impact factor: 6.303

3.  The phylogeny of the mammalian heme peroxidases and the evolution of their diverse functions.

Authors:  Noeleen B Loughran; Brendan O'Connor; Ciarán O'Fágáin; Mary J O'Connell
Journal:  BMC Evol Biol       Date:  2008-03-27       Impact factor: 3.260
  3 in total

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