Literature DB >> 10827873

Leprosy in China: delay in the detection of cases.

X S Chen1, W Z Li, C Jiang, G Y Ye.   

Abstract

In a national survey in China, 27,928 cases of leprosy detected by the health authorities between 1984 and 1998 were investigated. The delay between onset of symptoms (estimated from each case's recall) and confirmed diagnosis was < or = 2 years for 55.1% of the new patients but > 10 years for 7.0%, with a median value, overall, of 22.0 months. The median delay was longer: (1) for the multibacillary cases than the paucibacillary; (2) among farmers than among factory workers; (3) among some nationalities than among others (being longest among the Tu and shortest among the Wei); and (4) for some methods of case-detection than for others. Over the study period, the mean delay decreased with time. The delay was greatest in the areas where leprosy was endemic and/or where access to health services was poor. The later the cases were detected the more likely they were to show disability. Leprosy cases are still going undetected in China, although, over the last 14 years, case-finding has significantly improved. Age, occupation, nationality, leprosy type and detection method all appear to affect the delay.

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Year:  2000        PMID: 10827873     DOI: 10.1080/00034980057527

Source DB:  PubMed          Journal:  Ann Trop Med Parasitol        ISSN: 0003-4983


  9 in total

1.  Evaluation of various cytokines elicited during antigen-specific recall as potential risk indicators for the differential development of leprosy.

Authors:  L H Sampaio; A L M Sousa; M C Barcelos; S G Reed; M M A Stefani; M S Duthie
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2011-11-12       Impact factor: 3.267

2.  Transmission of leprosy in Qiubei County, Yunnan, China: insights from an 8-year molecular epidemiology investigation.

Authors:  Xiaoman Weng; Jason Vander Heiden; Yan Xing; Jian Liu; Varalakshmi Vissa
Journal:  Infect Genet Evol       Date:  2010-12-01       Impact factor: 3.342

3.  Molecular, ethno-spatial epidemiology of leprosy in China: novel insights for tracing leprosy in endemic and non endemic provinces.

Authors:  Xiaoman Weng; Yan Xing; Jian Liu; Yonghong Wang; Yong Ning; Ming Li; Wenbin Wu; Lianhua Zhang; Wei Li; Jason Vander Heiden; Varalakshmi Vissa
Journal:  Infect Genet Evol       Date:  2013-01-04       Impact factor: 3.342

Review 4.  Advances and hurdles on the way toward a leprosy vaccine.

Authors:  Malcolm S Duthie; Thomas P Gillis; Steven G Reed
Journal:  Hum Vaccin       Date:  2011-11-01

5.  Rapid quantitative serological test for detection of infection with Mycobacterium leprae, the causative agent of leprosy.

Authors:  Malcolm S Duthie; Marivic F Balagon; Armi Maghanoy; Florenda M Orcullo; Marjorie Cang; Ronaldo Ferreira Dias; Marco Collovati; Steven G Reed
Journal:  J Clin Microbiol       Date:  2013-12-11       Impact factor: 5.948

6.  Early Revelation of Leprosy in China by Sequential Antibody Analyses with LID-1 and PGL-I.

Authors:  Pan Qiong-Hua; Zheng Zhong-Yi; Yang Jun; Wen Yan; Yuan Lian-Chao; Li Huan-Ying; Steven G Reed; Malcolm S Duthie
Journal:  J Trop Med       Date:  2013-01-28

7.  Evaluation of novel tools to facilitate the detection and characterization of leprosy patients in China.

Authors:  Yan Wen; Yuan Gang You; Lian-Chao Yuan; You Hua Yuan; Ying Zhang; Malcolm S Duthie; Huan-Ying Li
Journal:  Biomed Res Int       Date:  2014-08-12       Impact factor: 3.411

8.  Delayed detection of leprosy cases: A systematic review of healthcare-related factors.

Authors:  Yudhy Dharmawan; Ahmad Fuady; Ida J Korfage; Jan Hendrik Richardus
Journal:  PLoS Negl Trop Dis       Date:  2022-09-06

9.  Delayed Diagnosis, Leprosy Reactions, and Nerve Injury Among Individuals With Hansen's Disease Seen at a United States Clinic.

Authors:  Kristoffer E Leon; Jesse T Jacob; Carlos Franco-Paredes; Phyllis E Kozarsky; Henry M Wu; Jessica K Fairley
Journal:  Open Forum Infect Dis       Date:  2016-03-25       Impact factor: 3.835

  9 in total

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