Literature DB >> 10827447

Positioning the isthmic organizer where Otx2 and Gbx2meet.

A Simeone1.   

Abstract

Regional diversity along the anterior-posterior axis of the central nervous system is established during gastrulation and is subsequently refined by local organizing centres that are located at genetically defined positions. The isthmic organizer possesses midbrain- and cerebellum-inducing properties, and its positioning at the midbrain-hindbrain boundary is a crucial event that controls midbrain and cerebellum development. Recent work has shown that two transcription factors, Otx2 and Gbx2, are instrumental in positioning the isthmic organizer at the midbrain-hindbrain boundary.

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Year:  2000        PMID： 10827447     DOI： 10.1016/s0168-9525(00)02000-x

Source DB:  PubMed          Journal:  Trends Genet        ISSN： 0168-9525            Impact factor:   11.639


  38 in total

1.  Hes1 and Hes3 regulate maintenance of the isthmic organizer and development of the mid/hindbrain.

Authors:  H Hirata; K Tomita; Y Bessho; R Kageyama
Journal:  EMBO J       Date:  2001-08-15       Impact factor: 11.598

2.  Ontogeny-recapitulating generation and tissue integration of ES cell-derived Purkinje cells.

Authors:  Keiko Muguruma; Ayaka Nishiyama; Yuichi Ono; Hiroyuki Miyawaki; Eri Mizuhara; Seiji Hori; Akira Kakizuka; Kunihiko Obata; Yuchio Yanagawa; Tomoo Hirano; Yoshiki Sasai
Journal:  Nat Neurosci       Date:  2010-09-12       Impact factor: 24.884

3.  Gbx2 and Otx2 interact with the WD40 domain of Groucho/Tle corepressors.

Authors:  Thomas Heimbucher; Christina Murko; Baubak Bajoghli; Narges Aghaallaei; Anja Huber; Ronald Stebegg; Dirk Eberhard; Maria Fink; Antonio Simeone; Thomas Czerny
Journal:  Mol Cell Biol       Date:  2006-10-23       Impact factor: 4.272

4.  Gbx2 directly restricts Otx2 expression to forebrain and midbrain, competing with class III POU factors.

Authors:  Fumitaka Inoue; Daisuke Kurokawa; Maiko Takahashi; Shinichi Aizawa
Journal:  Mol Cell Biol       Date:  2012-05-07       Impact factor: 4.272

5.  Signaling with homeoprotein transcription factors in development and throughout adulthood.

Authors:  A Prochiantz
Journal:  Curr Genomics       Date:  2013-09       Impact factor: 2.236

6.  The posteriorizing gene Gbx2 is a direct target of Wnt signalling and the earliest factor in neural crest induction.

Authors:  Bo Li; Sei Kuriyama; Mauricio Moreno; Roberto Mayor
Journal:  Development       Date:  2009-10       Impact factor: 6.868

7.  Wnt signaling regulates neural plate patterning in distinct temporal phases with dynamic transcriptional outputs.

Authors:  David G Green; Amy E Whitener; Saurav Mohanty; Brandon Mistretta; Preethi Gunaratne; Alvin T Yeh; Arne C Lekven
Journal:  Dev Biol       Date:  2020-03-31       Impact factor: 3.582

Review 8.  Desire, disease, and the origins of the dopaminergic system.

Authors:  Roy V Sillitoe; Michael W Vogel
Journal:  Schizophr Bull       Date:  2008-02-17       Impact factor: 9.306

9.  Xenopus Xotx2 and Drosophila otd share similar activities in anterior patterning of the frog embryo.

Authors:  Andrea Lunardi; Robert Vignali
Journal:  Dev Genes Evol       Date:  2006-03-11       Impact factor: 0.900

10.  Zebrafish gbx1 refines the midbrain-hindbrain boundary border and mediates the Wnt8 posteriorization signal.

Authors:  Muriel Rhinn; Klaus Lun; Reiner Ahrendt; Michaela Geffarth; Michael Brand
Journal:  Neural Dev       Date:  2009-04-02       Impact factor: 3.842
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