| Literature DB >> 10827427 |
A M Dondorp1, P A Kager, J Vreeken, N J White.
Abstract
Obstruction of the microcirculation plays a central role in the pathophysiology of severe malaria. Here, Arjen Dondorp and colleagues describe the various contributors to impaired microcirculatory flow in falciparum malaria: sequestration, rosetting and recent findings regarding impaired red blood cell deformability. The correlation with clinical findings and possible therapeutic consequences are discussed.Entities:
Mesh：
Year: 2000 PMID： 10827427 DOI： 10.1016/s0169-4758(00)01666-5
Source DB: PubMed Journal: Parasitol Today ISSN： 0169-4758