Literature DB >> 10826973

Molecular evolution: dynamic combinatorial libraries, autocatalytic networks and the quest for molecular function.

G R Cousins1, S A Poulsen, J K Sanders.   

Abstract

The principles of Darwinian evolution have been explored in molecular systems such as autocatalytic networks and dynamic combinatorial libraries. Molecular evolution in such systems manifests itself as ligand or receptor amplification by selection. Research efforts exploring these concepts may provide a mechanism for the identification of novel catalysts, molecular receptors and bioactive molecules.

Mesh:

Year:  2000        PMID: 10826973     DOI: 10.1016/s1367-5931(00)00088-0

Source DB:  PubMed          Journal:  Curr Opin Chem Biol        ISSN: 1367-5931            Impact factor:   8.822


  14 in total

Review 1.  Composing life.

Authors:  D Segré; D Lancet
Journal:  EMBO Rep       Date:  2000-09       Impact factor: 8.807

2.  Toward complex matter: supramolecular chemistry and self-organization.

Authors:  Jean-Marie Lehn
Journal:  Proc Natl Acad Sci U S A       Date:  2002-04-02       Impact factor: 11.205

3.  Target-induced formation of neuraminidase inhibitors from in vitro virtual combinatorial libraries.

Authors:  Matthias Hochgürtel; Heiko Kroth; Dorothea Piecha; Michael W Hofmann; Claude Nicolau; Sonja Krause; Otmar Schaaf; Gabriele Sonnenmoser; Alexey V Eliseev
Journal:  Proc Natl Acad Sci U S A       Date:  2002-03-12       Impact factor: 11.205

4.  Dynamic chemical devices: modulation of contraction/extension molecular motion by coupled-ion binding/pH change-induced structural switching.

Authors:  Mihail Barboiu; Jean-Marie Lehn
Journal:  Proc Natl Acad Sci U S A       Date:  2002-04-09       Impact factor: 11.205

5.  Self-replication: spelling it out in a chemical background.

Authors:  Wentao Ma; Chunwu Yu; Wentao Zhang; Ping Zhou; Jiming Hu
Journal:  Theory Biosci       Date:  2010-12-21       Impact factor: 1.919

6.  Kinetic analysis of self-replicating peptides: possibility of chiral amplification in open systems.

Authors:  Jesús Rivera Islas; Jean-Claude Micheau; Thomas Buhse
Journal:  Orig Life Evol Biosph       Date:  2004-10       Impact factor: 1.950

7.  Direct screening of a dynamic combinatorial library using mass spectrometry.

Authors:  Sally-Ann Poulsen
Journal:  J Am Soc Mass Spectrom       Date:  2006-06-02       Impact factor: 3.109

8.  Origins and emergent evolution of life: the colloid microsphere hypothesis revisited.

Authors:  Richard Egel
Journal:  Orig Life Evol Biosph       Date:  2014-09-11       Impact factor: 1.950

9.  Gelation-driven component selection in the generation of constitutional dynamic hydrogels based on guanine-quartet formation.

Authors:  Nampally Sreenivasachary; Jean-Marie Lehn
Journal:  Proc Natl Acad Sci U S A       Date:  2005-04-19       Impact factor: 11.205

10.  Self-organization by selection: generation of a metallosupramolecular grid architecture by selection of components in a dynamic library of ligands.

Authors:  Jonathan R Nitschke; Jean-Marie Lehn
Journal:  Proc Natl Acad Sci U S A       Date:  2003-09-29       Impact factor: 11.205

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