W C Lau1, W H Tam, W K Lo, P M Yuen. 1. Department of Obstetrics and Gynaecology, Prince of Wales Hospital, The Chinese University of Hong Kong.
Abstract
OBJECTIVE: To assess whether transcervical intrauterine instillation of local anaesthetic agent reduces pain during diagnostic outpatient hysteroscopy and endometrial biopsy. DESIGN: Prospective, randomised, double blind, placebo-controlled trial. SETTING:Outpatient hysteroscopy clinic in a university teaching hospital. POPULATION: Ninety women undergoing outpatient diagnostic hysteroscopy with or without endometrial biopsy. METHODS:Transcervical intrauterine instillation of 5 mL of 2% lignocaine into the uterine cavity before performing the procedure. MAIN OUTCOME MEASURES: Evaluation of pain at different stages of the procedure using a visual analogue scale and changes in blood pressure and heart rate. RESULTS: The use of local anaesthetic did not alleviate pain experienced during hysteroscopy and endometrial biopsy. It did not prevent the occurrence of vaso-vagal reactions; however the incidence of these was low. CONCLUSIONS:Transcervical instillation of local anaesthesia neither reduced pain nor prevented vaso-vagal reaction during hysteroscopy and endometrial biopsy.
RCT Entities:
OBJECTIVE: To assess whether transcervical intrauterine instillation of local anaesthetic agent reduces pain during diagnostic outpatient hysteroscopy and endometrial biopsy. DESIGN: Prospective, randomised, double blind, placebo-controlled trial. SETTING:Outpatient hysteroscopy clinic in a university teaching hospital. POPULATION: Ninety women undergoing outpatient diagnostic hysteroscopy with or without endometrial biopsy. METHODS: Transcervical intrauterine instillation of 5 mL of 2% lignocaine into the uterine cavity before performing the procedure. MAIN OUTCOME MEASURES: Evaluation of pain at different stages of the procedure using a visual analogue scale and changes in blood pressure and heart rate. RESULTS: The use of local anaesthetic did not alleviate pain experienced during hysteroscopy and endometrial biopsy. It did not prevent the occurrence of vaso-vagal reactions; however the incidence of these was low. CONCLUSIONS: Transcervical instillation of local anaesthesia neither reduced pain nor prevented vaso-vagal reaction during hysteroscopy and endometrial biopsy.