Literature DB >> 10825981

Total synthesis of (+/-)-isoschizogamine.

J L Hubbs1, C H Heathcock.   

Abstract

[formula: see text] Isoschizogamine has been prepared for the first time. The synthesis requires eight steps from a readily available ketone starting material and features an aminal-forming cyclization that is based on a proposed biosynthetic transformation.

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Year:  1999        PMID： 10825981     DOI： 10.1021/ol9902632

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  4 in total

1.  Facile Access to Ring-Fused Aminals via Direct α-Amination of Secondary Amines with ortho-Aminobenzaldehydes. Synthesis of Vasicine, Deoxyvasicine, Deoxyvasicinone, Mackinazolinone and Ruteacarpine.

Authors:  Matthew T Richers; Indubhusan Deb; Alena Yu Platonova; Chen Zhang; Daniel Seidel
Journal:  Synthesis (Stuttg)       Date:  2013-10-06       Impact factor: 3.157

2.  Metal-free α-amination of secondary amines: computational and experimental evidence for azaquinone methide and azomethine ylide intermediates.

Authors:  Arne Dieckmann; Matthew T Richers; Alena Yu Platonova; Chen Zhang; Daniel Seidel; K N Houk
Journal:  J Org Chem       Date:  2013-04-02       Impact factor: 4.354

3.  Synthesis and Reactions of Benzannulated Spiroaminals: Tetrahydrospirobiquinolines.

Authors:  Joshua Almond-Thynne; Andrew J P White; Anastasios Polyzos; Henry S Rzepa; Philip J Parsons; Anthony G M Barrett
Journal:  ACS Omega       Date:  2017-07-07

4.  Gold-catalyzed (4 + 2)-annulations between α-alkyl alkenylgold carbenes and benzisoxazoles with reactive alkyl groups.

Authors:  Bhanudas Dattatray Mokar; Prakash D Jadhav; Y B Pandit; Rai-Shung Liu
Journal:  Chem Sci       Date:  2018-04-23       Impact factor: 9.825
  4 in total

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