Literature DB >> 10825742

Molecular insights into the immunopathogenesis of follicular lymphoma.

K Stamatopoulos1, C Kosmas, C Belessi, N Stavroyianni, P Kyriazopoulos, T Papadaki.   

Abstract

Follicular lymphoma is caused by the transformation of a germinal-center-derived B cell with a t(14;18) chromosomal translocation. The distribution of somatic mutations within immunoglobulin genes indicates that follicular-lymphoma cells can interact with antigen. In addition, nonimmunoglobulin genes such as BCL6 seem to undergo somatic hypermutation. Here, Kostas Stamatopoulos and colleagues relate the molecular data about immunoglobulin genes and the protooncogenes BCL2 and BCL6 to the pathogenesis and evolution of follicular lymphoma.

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Year:  2000        PMID： 10825742     DOI： 10.1016/s0167-5699(00)01650-9

Source DB:  PubMed          Journal:  Immunol Today        ISSN： 0167-5699


  9 in total

1.  Composite follicular lymphoma and nodular lymphocyte predominance Hodgkin's disease.

Authors:  Jean-Louis Dargent; Laurence Lespagnard; Isabelle Meiers; Christophe Bradstreet; Pierre Heimann; Christiane De Wolf-Peeters
Journal:  Virchows Arch       Date:  2005-10-19       Impact factor: 4.064

2.  Somatic hypermutation analysis in follicular lymphoma provides evidence suggesting bidirectional cell migration between lymph node and bone marrow during disease progression and relapse.

Authors:  Martin Wartenberg; Peter Vasil; Christian Meyer zum Bueschenfelde; German Ott; Andreas Rosenwald; Falko Fend; Marcus Kremer
Journal:  Haematologica       Date:  2013-04-12       Impact factor: 9.941

3.  Unusual IgD+/CD38-follicular lymphoma with leukemic presentation.

Authors:  Grzegorz Rymkiewicz; Ewa Paszkiewicz-Kozik; Katarzyna Blachnio; Anna Pastwiska; Jadwiga Kulik; Barbara Pienkowska-Grela; Jan Walewski
Journal:  Med Oncol       Date:  2006       Impact factor: 3.064

4.  Point mutation of 5' noncoding region of BCL-6 gene in primary gastric lymphomas.

Authors:  Da-Liu Min; Xiao-Yan Zhou; Wen-Tao Yang; Hong-Fen Lu; Tai-Ming Zhang; Ai-Hua Zhen; Pei-Zheng Cao; Da-Ren Shi
Journal:  World J Gastroenterol       Date:  2005-01-07       Impact factor: 5.742

Review 5.  The classification of lymphomas: a new beginning or the end of an era?

Authors:  A S Jack
Journal:  Eur J Nucl Med Mol Imaging       Date:  2003-05-07       Impact factor: 9.236

6.  V(D)J-mediated translocations in lymphoid neoplasms: a functional assessment of genomic instability by cryptic sites.

Authors:  Rodrig Marculescu; Trang Le; Paul Simon; Ulrich Jaeger; Bertrand Nadel
Journal:  J Exp Med       Date:  2002-01-07       Impact factor: 14.307

7.  Heterogeneous breakpoints on the immunoglobulin genes are involved in fusion with the 5' region of BCL2 in B-cell tumors.

Authors:  N Yonetani; C Ueda; T Akasaka; M Nishikori; T Uchiyama; H Ohno
Journal:  Jpn J Cancer Res       Date:  2001-09

Review 8.  Infections and Follicular Lymphoma: is there a Link?

Authors:  Francesco Zallio; Giulia Limberti; Marco Ladetto
Journal:  Mediterr J Hematol Infect Dis       Date:  2017-05-01       Impact factor: 2.576

Review 9.  B Cell Receptor Immunogenetics in B Cell Lymphomas: Immunoglobulin Genes as Key to Ontogeny and Clinical Decision Making.

Authors:  Katerina Gemenetzi; Andreas Agathangelidis; Laura Zaragoza-Infante; Electra Sofou; Maria Papaioannou; Anastasia Chatzidimitriou; Kostas Stamatopoulos
Journal:  Front Oncol       Date:  2020-01-31       Impact factor: 6.244
  9 in total

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