Literature DB >> 10824988

DNA interaction with rabbit sperm cells and its transfer into ova in vitro and in vivo.

A V Kuznetsov1, I V Kuznetsova, I Y Schit.   

Abstract

Exogenous DNA interaction with rabbit sperm cells and its transfer into ova has been studied. It was shown that rabbit sperm cells are able to capture, hold, and transfer exogenous DNA to ova during fertilization. Sperm/DNA transfer leads to genetically transformed offspring. Transfection efficiency varied within a large range. Low expression and rearrangements of the transgene were observed.

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Year:  2000        PMID： 10824988     DOI： 10.1002/(SICI)1098-2795(200006)56:2+<292::AID-MRD18>3.0.CO;2-Z

Source DB:  PubMed          Journal:  Mol Reprod Dev        ISSN： 1040-452X            Impact factor:   2.609


  3 in total

1.  Increased transgene integration efficiency upon microinjection of DNA into both pronuclei of rabbit embryos.

Authors:  Peter Chrenek; Dusan Vasicek; Alexander V Makarevich; Rastislav Jurcik; Karin Suvegova; Vladimir Parkanyi; Miroslav Bauer; Jan Rafay; Angelika Batorova; Rekha K Paleyanda
Journal:  Transgenic Res       Date:  2005-08       Impact factor: 2.788

2.  Transgene transmission in chickens by sperm-mediated gene transfer after seminal plasma removal and exogenous DNA treated with dimethylsulfoxide or N,N-dimethylacetamide.

Authors:  Tiago Collares; Vinicius Farias Campos; Priscila Marques De Leon; Paulo V Cavalcanti; Marta G Amaral; Odir A Dellagostin; Joao Carlos Deschamps; Fabiana K Seixas
Journal:  J Biosci       Date:  2011-09       Impact factor: 1.826

3.  Production of transgenic pigs mediated by pseudotyped lentivirus and sperm.

Authors:  Yongliang Zhang; Qianyun Xi; Jinghua Ding; Weiguang Cai; Fanmin Meng; Junyun Zhou; Hongyi Li; Qingyan Jiang; Gang Shu; Songbo Wang; Xiaotong Zhu; Ping Gao; Zhenfang Wu
Journal:  PLoS One       Date:  2012-04-20       Impact factor: 3.240
  3 in total

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