Literature DB >> 1082439

Requirement for T cells in the antibody response of mice to calf skin collagen.

H Nowack, E Hahn, R Timpl.   

Abstract

The antibody response to triple-helical calf skin collagen is apparently regulated by T cells since nude mice (BALB/c strain) responded to this antigen only after transfer of T cells. Syngeneic transfer of B and T cells was required to prepare thymectomized and irradiated normal C57B1/10 recipients for an anti-collagen response. Reconstitution by B cells alone was unsuccessful. The results are compatible with previous evidence on the H-2 linked genetic control of the antibody response to and the non-repetitious nature of helical antigenic determinants in calf collagen.

Entities:  

Mesh：

Substances：

Year:  1976        PMID： 1082439      PMCID： PMC1444952     

Source DB:  PubMed          Journal:  Immunology        ISSN： 0019-2805            Impact factor:   7.397


  13 in total

Review 1.  T cell control of antibody production.

Authors:  R K Gershon
Journal:  Contemp Top Immunobiol       Date:  1974

2.  Chicken antibodies to soluble rat collagen. I. Characterization of the immune response by precipitation and agglutination methods.

Authors:  W Beil; H Furthmayr; R Timpl
Journal:  Immunochemistry       Date:  1972-08

Review 3.  T cell modification of B cell responses to antigen in mice.

Authors:  G F Mitchell
Journal:  Contemp Top Immunobiol       Date:  1974

Review 4.  The chemistry and structure of collagen.

Authors:  W Traub; K A Piez
Journal:  Adv Protein Chem       Date:  1971

5.  Induction of cell-mediated immunity and tolerance to homologous collagen in guinea pigs: demonstration of antigen-reactive cells for a self-antigen.

Authors:  G Senyk; D Michaeli
Journal:  J Immunol       Date:  1973-11       Impact factor: 5.422

6.  The structural basis of cell-mediated immunological reactions of collagen. Characteristics of cutaneous delayed hypersensitivity reactions in specifically sensitized guinea-pigs.

Authors:  B C Adelmann; J A Kirrane; L E Glynn
Journal:  Immunology       Date:  1972-11       Impact factor: 7.397

7.  Specificity of the antibody response in inbred mice to bovine type I and type II collagen.

Authors:  H Nowack; E Hahn; R Timpl
Journal:  Immunology       Date:  1975-10       Impact factor: 7.397

8.  Thymus-independence of slowly metabolized immunogens.

Authors:  M Sela; E Mozes; G M Shearer
Journal:  Proc Natl Acad Sci U S A       Date:  1972-09       Impact factor: 11.205

9.  The relationship between antigenic structure and the requirement for thymus-derived cells in the immune response.

Authors:  M Feldmann; A Easten
Journal:  J Exp Med       Date:  1971-07-01       Impact factor: 14.307

10.  Thymus independence of a collagen-like synthetic polypeptide and of collagen, and the need for thymus and bone marrow-cell cooperation in the immune response to gelatin.

Authors:  S Fuchs; E Mozes; A Maoz; M Sela
Journal:  J Exp Med       Date:  1974-01-01       Impact factor: 14.307
View more
  1 in total

1.  Administration of interleukin 12 in combination with type II collagen induces severe arthritis in DBA/1 mice.

Authors:  T Germann; J Szeliga; H Hess; S Störkel; F J Podlaski; M K Gately; E Schmitt; E Rüde
Journal:  Proc Natl Acad Sci U S A       Date:  1995-05-23       Impact factor: 11.205
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.