Literature DB >> 10823208

A facile method for the solution and solid-phase synthesis of substituted [3.3.1] bicycles.

K C Nicolaou1, J A Pfefferkorn, G Q Cao, S Kim, J Kessabi.   

Abstract

[reaction: see text] Interest in bicyclic natural products from the Guttiferae classification has led to the development of an improved method for the selenium-mediated cyclization of alkenyl-substituted beta-dicarbonyls (I) to form a variety of bicyclo[3.3.1]nonan-9-ones (II) both in solution and on solid support.

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Year:  1999        PMID: 10823208     DOI: 10.1021/ol990791d

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  2 in total

1.  Asymmetric, stereodivergent synthesis of (-)-clusianone utilizing a biomimetic cationic cyclization.

Authors:  Jonathan H Boyce; John A Porco
Journal:  Angew Chem Int Ed Engl       Date:  2014-06-10       Impact factor: 15.336

Review 2.  From polymer to small organic molecules: a tight relationship between radical chemistry and solid-phase organic synthesis.

Authors:  Danilo Mirizzi; Maurizio Pulici
Journal:  Molecules       Date:  2011-04-18       Impact factor: 4.411

  2 in total

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