Literature DB >> 1082263

The influence of bretylium tosylate on the intraocular pressure of the rabbit.

G K Krieglstein.   

Abstract

Bretylium tosylate was applied topically and intravitreously to rabbit eyes. The topical application of 1, 2, 5 and 10% bretylium tosylate gave a small but significant decrease of the intraocular pressure 6 hrs after treatment. The effects had disappeared, when the eyes were re-examined after 24 hrs. The intravitreous injection of 200 mug of bretylium tosylate caused a more pronounced and prolonged pressure decrease. The results are interpreted in the light of chemical sympathectomy.

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Year:  1975        PMID: 1082263     DOI: 10.1007/bf02388781

Source DB:  PubMed          Journal:  Albrecht Von Graefes Arch Klin Exp Ophthalmol        ISSN: 0065-6100


  9 in total

1.  The influence of pre- and postganglionic section of the cervical sympathetic on the intraocular pressure of rabbits and cats.

Authors:  M E LANGHAM; C B TAYLOR
Journal:  J Physiol       Date:  1960-07       Impact factor: 5.182

2.  Chemical sympathectomy with 6-hydroxydopamine in the treatment of primary open-angle glaucoma.

Authors:  Y Kitazawa; H Nosé; T Horie
Journal:  Am J Ophthalmol       Date:  1975-01       Impact factor: 5.258

3.  The effect of topically applied guanethidine sulphate on pupil and tension responses of the rabbit eye to (--)-adrenaline bitartrate.

Authors:  J W Lamble
Journal:  Exp Eye Res       Date:  1974-07       Impact factor: 3.467

4.  Chemical sympathectomy in glaucoma therapy: an investigation of alpha and beta adrenergic supersensitivity.

Authors:  M G Holland; C P Wei
Journal:  Ann Ophthalmol       Date:  1973-07

5.  The mechanism of action of guanethidine on aqueous humor dynamics.

Authors:  E D Hendley; K E Eakins
Journal:  J Pharmacol Exp Ther       Date:  1965-12       Impact factor: 4.030

6.  The influence of topically applied bethanidine on intraocular pressure and pupil in the rabbit.

Authors:  G K Krieglstein
Journal:  Albrecht Von Graefes Arch Klin Exp Ophthalmol       Date:  1975-08-04

7.  The 24-hour-ganglionectomy effect in rabbits. The influence of partial iridectomy and of acetazolamide.

Authors:  A L Crombie; E D Hendley
Journal:  Exp Eye Res       Date:  1967-10       Impact factor: 3.467

8.  Bretylium tosylate for suppression of induced ventricular fibrillation.

Authors:  M Bacaner
Journal:  Am J Cardiol       Date:  1966-04       Impact factor: 2.778

9.  COMPARISON OF THE EFFECTS OF BRETYLIUM, GUANETHIDINE AND BETHANIDINE ON SMOOTH MUSCLE RESPONSES TO DIFFERENT RATES OF SYMPATHETIC NERVE STIMULATION.

Authors:  A F GREEN; R D ROBSON
Journal:  Br J Pharmacol Chemother       Date:  1964-04
  9 in total

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