Literature DB >> 10822533

Enantioselective aldol cyclodehydrations catalyzed by antibody 38C2.

B List1, R A Lerner, C F Barbas.   

Abstract

[formula: see text] Aldolase antibody 38C2 catalyzes the enantioselective aldol cyclodehydration of 4-substituted-2,6-heptanediones (3) to give enantiomerically enriched 5-substituted-3-methyl-2-cyclohexen-1-ones (4). Yields, enantioselectivities, and product purities are markedly increased compared to the L-proline-catalyzed reactions.

Entities:  

Mesh:

Substances:

Year:  1999        PMID: 10822533     DOI: 10.1021/ol9905405

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  1 in total

1.  Caged Proline in Photoinitiated Organocatalysis.

Authors:  Charitha Guruge; Saad Y Rfaish; Chanel Byrd; Shukun Yang; Anthony K Starrett; Eric Guisbert; Nasri Nesnas
Journal:  J Org Chem       Date:  2019-04-03       Impact factor: 4.354

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.