| Literature DB >> 10822533 |
B List1, R A Lerner, C F Barbas.
Abstract
[formula: see text] Aldolase antibody 38C2 catalyzes the enantioselective aldol cyclodehydration of 4-substituted-2,6-heptanediones (3) to give enantiomerically enriched 5-substituted-3-methyl-2-cyclohexen-1-ones (4). Yields, enantioselectivities, and product purities are markedly increased compared to the L-proline-catalyzed reactions.Entities:
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Year: 1999 PMID: 10822533 DOI: 10.1021/ol9905405
Source DB: PubMed Journal: Org Lett ISSN: 1523-7052 Impact factor: 6.005