Literature DB >> 10822131

Conventional tumor markers are prognostic indicators in patients with head and neck squamous cell carcinoma.

Y Kimura1, S Fujieda, T Takabayashi, T Tanaka, C Sugimoto, H Saito.   

Abstract

We tested for squamous cell carcinoma-related antigen (SCC), carcinoembryonic antigen (CEA), ferritin, immunosuppressive acid protein (IAP) and sialic acid in the serum from 247 patients with head and neck squamous cell carcinoma prior to therapy. Significant correlations were found between IAP and tumor size, lymph node metastasis, and clinical stage (P<0.0001, P<0.001, and P<0.0001). Also, sialic acid and SCC were also correlated with tumor size, lymph node metastasis, and clinical stage. Moreover IAP, sialic acid and SCC were strongly associated with survival rate (P<0.0001, P = 0.0230 and P = 0.0159). A multivariate Cox proportional hazard model demonstrated that being positive for IAP was an independent predictor for patients with H&NSCC (P = 0.0115). The results indicate that IAP, sialic acid and SCC are useful as prognostic factors.

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Year:  2000        PMID： 10822131     DOI： 10.1016/s0304-3835(00)00423-7

Source DB:  PubMed          Journal:  Cancer Lett        ISSN： 0304-3835            Impact factor:   8.679


  7 in total

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Authors:  I-How Chen; Chun-Ta Liao; Hung-Ming Wang; Jung-Ju Huang; Chung-Jan Kang; Shiang-Fu Huang
Journal:  PLoS One       Date:  2014-07-25       Impact factor: 3.240

2.  Diagnostic values of serum tumor markers Cyfra21-1, SCCAg, ferritin, CEA, CA19-9, and AFP in oral/oropharyngeal squamous cell carcinoma.

Authors:  Chuanshu Yuan; Kai Yang; Hong Tang; Dan Chen
Journal:  Onco Targets Ther       Date:  2016-06-03       Impact factor: 4.147

3.  Estimation of serum sialic acid in oral submucous fibrosis and oral squamous cell carcinoma.

Authors:  Samatha Chittemsetti; Praveen Kumar Manchikatla; Venkateswararao Guttikonda
Journal:  J Oral Maxillofac Pathol       Date:  2019 Jan-Apr

4.  Serum CD109 levels reflect the node metastasis status in head and neck squamous cell carcinoma.

Authors:  Sumitaka Hagiwara; Eiichi Sasaki; Yasuhisa Hasegawa; Hidenori Suzuki; Daisuke Nishikawa; Shintaro Beppu; Hoshino Terada; Michi Sawabe; Masahide Takahashi; Nobuhiro Hanai
Journal:  Cancer Med       Date:  2021-02-09       Impact factor: 4.452

5.  Significantly higher serum tumor marker levels in patients with oral submucous fibrosis.

Authors:  Yu-Hsueh Wu; Ping-Yi Lin; Ju-Hsuan Yang; Ying-Shiung Kuo; Yang-Che Wu; Chun-Pin Chiang
Journal:  J Dent Sci       Date:  2021-03-11       Impact factor: 2.080

6.  Quantitative evaluation and correlation of serum glycoconjugates: Protein bound hexoses, sialic acid and fucose in leukoplakia, oral sub mucous fibrosis and oral cancer.

Authors:  K Subhash Chandra Bose; Prerna Vyas Gokhale; Sunil Dwivedi; Manika Singh
Journal:  J Nat Sci Biol Med       Date:  2013-01

7.  Pre-treatment levels of C-reactive protein and squamous cell carcinoma antigen for predicting the aggressiveness of pharyngolaryngeal carcinoma.

Authors:  Hsuan-Ho Chen; Hung-Ming Wang; Kang-Hsing Fan; Chien-Yu Lin; Tzu-Chen Yen; Chun-Ta Liao; I-How Chen; Chung-Jan Kang; Shiang-Fu Huang
Journal:  PLoS One       Date:  2013-01-31       Impact factor: 3.240
  7 in total

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