Literature DB >> 10821371

Evidence for presence of IgG4 anti-immunoglobulin autoantibodies in all human beings.

C Hennig, L Rink, H Kirchner.   

Abstract

IgG4 anti-IgG autoantibodies were found to be present in all serum samples from a group of healthy people; IgG4 ant-IgA and anti-IgE were present In only 13 of 218 (6%) and 8 of 218 (3.5%) samples, respectively. These antibodies also showed affinities towards animal immunoglobulins. We suggest that IgG4 anti-IgA antibodies (the strongest found heterophilic Immunoglobulins) are responsible for most artifacts obtained with commercial EUSA systems.

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Year:  2000        PMID: 10821371     DOI: 10.1016/s0140-6736(00)02223-6

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  6 in total

1.  Examination of glycan profiles from IgG-depleted human immunoglobulins facilitated by microscale affinity chromatography.

Authors:  Martin Svoboda; Benjamin F Mann; John A Goetz; Milos V Novotny
Journal:  Anal Chem       Date:  2012-03-13       Impact factor: 6.986

2.  Frequent false positive beta human chorionic gonadotropin tests in immunoglobulin A deficiency.

Authors:  A K Knight; T Bingemann; L Cole; C Cunningham-Rundles
Journal:  Clin Exp Immunol       Date:  2005-08       Impact factor: 4.330

3.  M cell-targeted ocular immunization: effect on immunoglobulins in tears, feces, and serum.

Authors:  Thomas E Phillips; Jeremy Sharp; Kay Rodgers; Hongshan Liu
Journal:  Invest Ophthalmol Vis Sci       Date:  2009-11-05       Impact factor: 4.799

4.  IgG4 Autoantibodies Attenuate Systemic Lupus Erythematosus Progression by Suppressing Complement Consumption and Inflammatory Cytokine Production.

Authors:  Qingjun Pan; Haiyan Xiao; Lei Shi; Yiming He; Jun Cai; Jing Wu; Aifen Li; Lin Ye; Chen Yang; Hua-Feng Liu
Journal:  Front Immunol       Date:  2020-06-17       Impact factor: 7.561

5.  False-positive and false-negative COVID-19 cases: respiratory prevention and management strategies, vaccination, and further perspectives.

Authors:  Dimitra S Mouliou; Konstantinos I Gourgoulianis
Journal:  Expert Rev Respir Med       Date:  2021-04-25       Impact factor: 3.772

6.  A novel immunoglobulin-immunoglobulin interaction in autoimmunity.

Authors:  Shigeyuki Kawa; Kei Kitahara; Hideaki Hamano; Yayoi Ozaki; Norikazu Arakura; Kaname Yoshizawa; Takeji Umemura; Masao Ota; Sadaaki Mizoguchi; Yasunori Shimozuru; Seiamak Bahram
Journal:  PLoS One       Date:  2008-02-20       Impact factor: 3.240

  6 in total

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