| Literature DB >> 10821056 |
J K Hwang, T W Kong, N I Baek, Y R Pyun.
Abstract
Hexagalloylglucose (3-O-digalloyl-1,2,4,6-tetra-O-galloyl-beta-D- glucose), which was isolated from the methanol extract of the galls of Quercus infectoria, significantly inhibited alpha-glycosidases such as sucrase, maltase and isomaltase. Its inhibitory activity was comparable to acarbose being used as a hypoglycemic agent, while the inhibitory activity on alpha-amylase was approximately 10 times lower than that of acarbose. The results indicate that, when compared to acarbose, hexagalloylglucose might reduce the side effects by reducing inhibition of alpha-amylase.Entities:
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Year: 2000 PMID: 10821056 DOI: 10.1055/s-2000-8569
Source DB: PubMed Journal: Planta Med ISSN: 0032-0943 Impact factor: 3.352