Literature DB >> 10820831

Quaternary indole alkaloids from the stem bark of Strychnos guianensis.

J Penelle1, M Tits, P Christen, J Molgo, V Brandt, M Frédérich, L Angenot.   

Abstract

Two new quaternary alkaloids, 9-methoxy-Nb-methylgeissoschizol and guiachrysine together with the known compounds C-alkaloid O, fluorocurine, mavacurine, macusine B and C-profluorocurine, were isolated from Strychnos guianensis stembark. The structures of the compounds were elucidated on the basis of spectroscopic studies.

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Year:  2000        PMID： 10820831     DOI： 10.1016/s0031-9422(00)00033-9

Source DB:  PubMed          Journal:  Phytochemistry        ISSN： 0031-9422            Impact factor:   4.072


  6 in total

1.  Total synthesis of the opioid agonistic indole alkaloid mitragynine and the first total syntheses of 9-methoxygeissoschizol and 9-methoxy-Nb-methylgeissoschizol.

Authors:  Jun Ma; Wenyuan Yin; Hao Zhou; James M Cook
Journal:  Org Lett       Date:  2007-08-08       Impact factor: 6.005

2.  Bisindole alkaloids from Strychnos guianensis are effective antagonists of nicotinic acetylcholine receptors in cultured human TE671 cells.

Authors:  Pierre Wins; Ilca Margineanu; Jacques Penelle; Luc Angenot; Thierry Grisar; Lucien Bettendorff
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2003-02-19       Impact factor: 3.000

3.  General approach to the total synthesis of 9-methoxy-substituted indole alkaloids: synthesis of mitragynine, as well as 9-methoxygeissoschizol and 9-methoxy-N(b)-methylgeissoschizol.

Authors:  Jun Ma; Wenyuan Yin; Hao Zhou; Xuebin Liao; James M Cook
Journal:  J Org Chem       Date:  2009-01-02       Impact factor: 4.354

4.  Formal Alder-ene reaction of a bicyclo[1.1.0]butane in the synthesis of the tricyclic quaternary ammonium core of daphniglaucins.

Authors:  Masafumi Ueda; Maciej A A Walczak; Peter Wipf
Journal:  Tetrahedron Lett       Date:  2008-06       Impact factor: 2.415

Review 5.  Application of the Asymmetric Pictet-Spengler Reaction in the Total Synthesis of Natural Products and Relevant Biologically Active Compounds.

Authors:  Majid M Heravi; Vahideh Zadsirjan; Masumeh Malmir
Journal:  Molecules       Date:  2018-04-18       Impact factor: 4.411

Review 6.  Recent Advances in the Synthesis of β-Carboline Alkaloids.

Authors:  Tímea Szabó; Balázs Volk; Mátyás Milen
Journal:  Molecules       Date:  2021-01-27       Impact factor: 4.411
  6 in total

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