Literature DB >> 1081908

Assay for citrovorum factor (NSC-3590) in the presence of methotrexate (NSC-740).

B M Mehta, D J Hutchison.   

Abstract

Treatment of certain malignancies with high-dose methotrexate/citrovorum factor rescue has recently been adopted as an effective regimen. A microbiologic assay capable of detecting citrovorum factor in the presence of massive amounts of methotrexate has been developed using a strain of Pediococcus cerevisiae resistant to methotrexate. The assay described in this paper is an inexpensive and rapid method of studying the distribution kinetics of citrovorum factor.

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Year:  1975        PMID： 1081908

Source DB:  PubMed          Journal:  Cancer Chemother Rep        ISSN： 0069-0112


  3 in total

1.  Pharmacokinetics of reduced folates after short-term infusion of d, 1-folinic acid.

Authors:  A Schalhorn; M Kühl; G Stupp-Poutot; V Nüssler
Journal:  Cancer Chemother Pharmacol       Date:  1990       Impact factor: 3.333

2.  Plasma kinetic study of folinic acid and 5-methyltetrahydrofolate in healthy volunteers and cancer patients by high-performance liquid chromatography.

Authors:  B Payet; G Fabre; N Tubiana; J P Cano
Journal:  Cancer Chemother Pharmacol       Date:  1987       Impact factor: 3.333

3.  The pharmacokinetics of reduced folates after intraperitoneal and intravenous administration of racemic [6S,R]-folinic acid.

Authors:  J H Sips; O van Tellingen; W J Nooijen; S Rodenhuis; W J Ten Bokkel Huinink; J H Beijnen
Journal:  Cancer Chemother Pharmacol       Date:  1994       Impact factor: 3.333
  3 in total

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