Literature DB >> 10819035

[Effect of age and radiation exposure on the frequency of translocations and dicentrics detected by FISH method in human lymphocytes].

I E Vorobtsova1, J D Tucker, N M Timofeeva, A N Bogomazova, A V Semenov, P G Pleshanov.   

Abstract

The frequencies of translocations and dicentrics detected by "chromosome painting" in lymphocytes were estimated in 115 healthy donors and in 273 people exposed to uncontrolled irradiation at low doses 1-4 years ago. Age responses of both types of exchanges at the age range from 3 to 85 years fit to quadratic model. The frequency of translocations grew faster with age than the frequency of dicentrics. The yields of stable exchanges in exposed people was significantly higher than those in control donors of corresponding ages.

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Year:  2000        PMID: 10819035

Source DB:  PubMed          Journal:  Radiats Biol Radioecol        ISSN: 0869-8031


  2 in total

1.  International study of factors affecting human chromosome translocations.

Authors:  Alice J Sigurdson; Mina Ha; Michael Hauptmann; Parveen Bhatti; Radim J Sram; Olena Beskid; E Janet Tawn; Caroline A Whitehouse; Carita Lindholm; Mimako Nakano; Yoshiaki Kodama; Nori Nakamura; Irena Vorobtsova; Ursula Oestreicher; Günther Stephan; Lee C Yong; Manfred Bauchinger; Ernst Schmid; Hai Won Chung; Firouz Darroudi; Laurence Roy; Phillipe Voisin; Joan F Barquinero; Gordon Livingston; David Blakey; Isamu Hayata; Wei Zhang; Chunyan Wang; L Michelle Bennett; L Gayle Littlefield; Alan A Edwards; Ruth A Kleinerman; James D Tucker
Journal:  Mutat Res       Date:  2008-02-02       Impact factor: 2.433

2.  Chromosome analysis of nuclear power plant workers using fluorescence in situ hybridization and Giemsa assay.

Authors:  Rositsa Hristova; Valeria Hadjidekova; Mira Grigorova; Teodora Nikolova; Minka Bulanova; Ljubomira Popova; Albena Staynova; Donka Benova
Journal:  J Radiat Res       Date:  2013-03-27       Impact factor: 2.724

  2 in total

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