Literature DB >> 10819026

Group-specific component (Gc) subtypes in the Chinese population of Hong Kong.

K Y Kwok1, W H Lewis.   

Abstract

The distribution of Gc subtypes in a sample of the Chinese population of Hong Kong was studied using isoelectric focusing followed by immunofixation. A sensitive modification of this technique is described. Nine distinct phenotypes were observed which appear to result from the three common alleles Gc1F, Gc1S, and Gc2, which are found in most populations. The respective gene frequencies were 0.494, 0.258, and 0.247. In addition, two rare phenotypes were observed which appear to be due to a rare allele tentatively identified as Gc2C2.

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Year:  1981        PMID： 10819026     DOI： 10.1007/bf00278858

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  9 in total

1.  Group-specific component. Report on the First International Workshop, Collège de France--July 27-28, 1978--Paris.

Authors:  J Constans; H Cleve
Journal:  Hum Genet       Date:  1979-04-27       Impact factor: 4.132

2.  Gc subtypes demonstrated by isoelectric focusing: further data and description of new variants among an African sample (Fula) from Senegal.

Authors:  J Constans; M Viau; G Pison; A Langaney
Journal:  Jinrui Idengaku Zasshi       Date:  1978-06

3.  The distribution of the group-specific component (Gc) subtypes in Japanese.

Authors:  K Omoto; K Miyake
Journal:  Jinrui Idengaku Zasshi       Date:  1978-06

4.  Group-specific component: evidence for two subtypes of the Gc1 gene.

Authors:  J Constans; M Viau
Journal:  Science       Date:  1977-12-09       Impact factor: 47.728

5.  Analysis of the Gc polymorphism in human populations by isoelectrofocusing on polyacrylamide gels. Demonstration of subtypes of the Gc allele and of additional Gc variants.

Authors:  J Constans; M Viau; H Cleve; G Jaeger; J C Quilici; M J Palisson
Journal:  Hum Genet       Date:  1978-02-23       Impact factor: 4.132

6.  An improved method for the identification of Gc1 subtypes (group-specific component) by isoelectric focusing.

Authors:  P Kühnl; W Spielmann; M Loa
Journal:  Vox Sang       Date:  1978       Impact factor: 2.144

7.  Neuraminidase treatment reveals sialic acid differences in certain genetic variants of the Gc system (vitamin-D-binding protein).

Authors:  H Cleve; W Patutschnick
Journal:  Hum Genet       Date:  1979-03-12       Impact factor: 4.132

8.  Group-specific component (Gc) and transferrin (Tf) subtypes ascertained by isoelectric focusing. A simple nonimmunological staining procedure for Gc.

Authors:  B Hoste
Journal:  Hum Genet       Date:  1979       Impact factor: 4.132

9.  Group-specific component (Gc) proteins bind vitamin D and 25-hydroxyvitamin D.

Authors:  S P Daiger; M S Schanfield; L L Cavalli-Sforza
Journal:  Proc Natl Acad Sci U S A       Date:  1975-06       Impact factor: 11.205
  9 in total
  2 in total

Review 1.  Ethnic variation in vitamin D-binding protein (GC): a review of isoelectric focusing studies in human populations.

Authors:  M I Kamboh; R E Ferrell
Journal:  Hum Genet       Date:  1986-04       Impact factor: 4.132

2.  Population genetics of the vitamin D binding protein (GC) subtypes in the Asian-Pacific area: description of new alleles at the GC locus.

Authors:  M I Kamboh; P R Ranford; R L Kirk
Journal:  Hum Genet       Date:  1984       Impact factor: 4.132
  2 in total

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