| Literature DB >> 10818608 |
G Alves1, M T Kawamura, P Nascimento, C Maciel, J A Oliveira, A Teixeira, M da G Carvalho.
Abstract
We have verified the presence of line-1 retrotransposon (L1) in plasma DNA in 15/17 brain tumor (glioma) patients and in 6/6 healthy people by applying PCR amplification of part of the L1 5' end. The same samples were separately amplified for K-ras. Results suggested that L1 sequences are circulating throughout the body. We hypothesized the participation of transposable elements such as L1 in a putative DNA release mechanism.Entities:
Mesh：
Substances：
Year: 2000 PMID： 10818608 DOI： 10.1111/j.1749-6632.2000.tb06602.x
Source DB: PubMed Journal: Ann N Y Acad Sci ISSN： 0077-8923 Impact factor: 5.691