Literature DB >> 10817640

The role of interleukin 15 in mounting an immune response against microbial infections.

Y Yoshikai1, H Nishimura.   

Abstract

Interleukin (IL)-15 is a recently described cytokine that resembles IL-2 in its biological activities, stimulating natural killer cells, T cells and B cells to proliferate, secrete cytokines, and exhibit increased cytotoxicities or produce antibody. IL-15 also exerts unique functions such as stimulation of phagocytes, maintenance of mast cells and migration of activated/memory T cells. IL-15 is involved in protection against infections with a variety of microbes through not only activating innate immunity but also mounting adaptive immunity.

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Year:  2000        PMID： 10817640     DOI： 10.1016/s1286-4579(00)00329-4

Source DB:  PubMed          Journal:  Microbes Infect        ISSN： 1286-4579            Impact factor:   2.700


  7 in total

1.  A multi-valent vaccinia virus-based tuberculosis vaccine molecularly adjuvanted with interleukin-15 induces robust immune responses in mice.

Authors:  Pin-Yu Perera; Steven C Derrick; Kristopher Kolibab; Fumiki Momoi; Masafumi Yamamoto; Sheldon L Morris; Thomas A Waldmann; Liyanage P Perera
Journal:  Vaccine       Date:  2009-02-06       Impact factor: 3.641

2.  Hepatic interleuklin 15 (IL-15) expression: implications for local NK/NKT cell homeostasis and development.

Authors:  L Golden-Mason; A M Kelly; D G Doherty; O Traynor; G McEntee; J Kelly; J E Hegarty; C O'Farrelly
Journal:  Clin Exp Immunol       Date:  2004-10       Impact factor: 4.330

3.  The role of IL15 gene variants in visceral leishmaniasis among Iranian patients.

Authors:  Manoochehr Rasouli; Mehdi Kalani; Simin Kiany
Journal:  Mol Biol Rep       Date:  2013-05-07       Impact factor: 2.316

4.  IL-15 augments TCR-induced CD4+ T cell expansion in vitro by inhibiting the suppressive function of CD25 High CD4+ T cells.

Authors:  Tom L Van Belle; Hans Dooms; Tom Boonefaes; Xiao-Qing Wei; Georges Leclercq; Johan Grooten
Journal:  PLoS One       Date:  2012-09-20       Impact factor: 3.240

5.  Host genetic variants of ABCB1 and IL15 influence treatment outcome in paediatric acute lymphoblastic leukaemia.

Authors:  Y Lu; S K Y Kham; H Ariffin; A M I Oei; H P Lin; A M Tan; T C Quah; A E J Yeoh
Journal:  Br J Cancer       Date:  2014-01-16       Impact factor: 7.640

6.  Combined in vitro IL-12 and IL-15 stimulation promotes cellular immune response in dogs with visceral leishmaniasis.

Authors:  Sidnei Ferro Costa; Vinícius Oliveira Gomes; Marilene Oliveira Dos Santos Maciel; Larissa Martins Melo; Gabriela Lovizutto Venturin; Jaqueline Poleto Bragato; Gabriela Torres Rebech; Catiule de Oliveira Santos; Bárbara Maria Nascimento de Oliveira; Geraldo Gileno de Sá Oliveira; Valéria Marçal Felix de Lima
Journal:  PLoS Negl Trop Dis       Date:  2020-01-21

7.  IL-15Rα-Independent IL-15 Signaling in Non-NK Cell-Derived IFNγ Driven Control of Listeria monocytogenes.

Authors:  Madhuparna Nandi; Mitterrand Muamba Moyo; Sakina Orkhis; Jeanne Masunga Faida Mobulakani; Marc-André Limoges; Fjolla Rexhepi; Marian Mayhue; Anny Armas Cayarga; Gisela Cofino Marrero; Subburaj Ilangumaran; Alfredo Menendez; Sheela Ramanathan
Journal:  Front Immunol       Date:  2021-12-10       Impact factor: 7.561
  7 in total

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