Literature DB >> 10815578

Witkop tooth and nail syndrome: report of two cases in a family.

S J Hodges1, K E Harley.   

Abstract

Tooth and nail syndrome, an autosomal dominant condition, is characterized by hypodontia and nail dysplasia. Mandibular incisors, second molars and maxillary canines are the most frequently missing teeth. Tooth shape may vary and conical and narrow crowns are common. Nail dysplasia affects fingernails and toenails and is often more severe in childhood. Nails may be spoon-shaped, ridged, slow growing and easily broken. The clinical and radiographic features of a father and son presenting with this rare condition are described.

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Year:  1999        PMID: 10815578     DOI: 10.1046/j.1365-263x.1999.00128.x

Source DB:  PubMed          Journal:  Int J Paediatr Dent        ISSN: 0960-7439            Impact factor:   3.455


  2 in total

1.  A nonsense mutation in MSX1 causes Witkop syndrome.

Authors:  D Jumlongras; M Bei; J M Stimson; W F Wang; S R DePalma; C E Seidman; U Felbor; R Maas; J G Seidman; B R Olsen
Journal:  Am J Hum Genet       Date:  2001-05-16       Impact factor: 11.025

2.  Surgical and prosthetic rehabilitation of siblings with Witkop tooth and nail syndrome using zygomatic implants: a familial case series of 3 patients with up to 15-year follow-up.

Authors:  Kale B McMillan; Dane C McMillan; Kevin Arce; Thomas J Salinas
Journal:  Oral Maxillofac Surg       Date:  2022-07-30
  2 in total

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