Literature DB >> 10814433

Cobalt-Induced C-N and C-C Bond Formation via Metal-Stabilized alpha-CF(3) Carbenium Ion.

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Abstract

An alpha-CF(3)-carbenium ion stabilized by a bimetallic [Co-Co] cluster was prepared and isolated in good yield, starting from the corresponding alcohol by action of HBF(4)/Et(2)O. C-N and C-C bonds with nitrogen and carbon nucleophiles could be easily formed. Subsequent decomplexation gave the free substituted beta-CF(3) alkynes in good yields.

Entities:  

Year:  2000        PMID： 10814433     DOI： 10.1021/ol005554l

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  3 in total

1.  Alkyne Ligation Handles: Propargylation of Hydroxyl, Sulfhydryl, Amino, and Carboxyl Groups via the Nicholas Reaction.

Authors:  Sarah M Wells; John C Widen; Daniel A Harki; Kay M Brummond
Journal:  Org Lett       Date:  2016-08-29       Impact factor: 6.005

2.  Generation and Reactions of a Benzodehydrotropylium Ion-Co2(CO)6 Complex.

Authors:  Mariam A Mehdi; Eric A C Bushnell; Sahar Nikoo; James W Gauld; James R Green
Journal:  ACS Omega       Date:  2019-10-28

Review 3.  CF3-substituted carbocations: underexploited intermediates with great potential in modern synthetic chemistry.

Authors:  Anthony J Fernandes; Armen Panossian; Bastien Michelet; Agnès Martin-Mingot; Frédéric R Leroux; Sébastien Thibaudeau
Journal:  Beilstein J Org Chem       Date:  2021-02-03       Impact factor: 2.883
  3 in total

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