| Literature DB >> 10814365 |
L C Chang1, D Chávez, L L Song, N R Farnsworth, J M Pezzuto, A D Kinghorn.
Abstract
[structure: see text] Three novel flavonoids, (+)-tephrorins A (1) and B (2) and (+)-tephrosone (3), were isolated from Tephrosia purpurea. Their structures were elucidated by NMR spectral analysis, and their absolute configurations were determined by Mosher ester methodology. Compounds 1 and 2 are flavanones containing an unusual tetrahydrofuran moiety. Compounds 1-3 were evaluated for their potential cancer chemopreventive properties using a cell-based quinone reductase induction assay.Entities:
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Year: 2000 PMID： 10814365 DOI： 10.1021/ol990407c
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005