Literature DB >> 10814343

Novel one-step synthesis of thiazolo[3,2-b]1,2,4-triazoles.

A R Katritzky1, A Pastor, M Voronkov, P J Steel.   

Abstract

[reaction: see text] Reactions of chalcones 3a-f with bis(1H-1,2,4-triazolyl) sulfoxide 4 formed the thiazolo[3,2-b]1,2,4-triazoles 5a-f, which resemble closely some previously prepared COX-2 inhibitors. The structure of 5a was confirmed by X-ray analysis.

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Year:  2000        PMID: 10814343     DOI: 10.1021/ol990370w

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  1 in total

1.  Regioselectivity in Sonogashira synthesis of 6-(4-nitrobenzyl)-2-phenylthiazolo[3,2-b]1,2,4-triazole: a quantum chemistry study.

Authors:  Tayebeh Hosseinnejad; Majid M Heravi; Rohoullah Firouzi
Journal:  J Mol Model       Date:  2012-10-25       Impact factor: 1.810

  1 in total

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