Literature DB >> 10814307

Design and synthesis of novel conformationally restricted peptide secondary structure mimetics

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Abstract

[structure: see text] A facile synthesis of the novel conformationally restricted reverse turn mimetic is described. The key features are the preparation of the alpha-keto amide and tandem bicyclic ring formation.

Entities:  

Year:  2000        PMID： 10814307     DOI： 10.1021/ol990355r

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  4 in total

1.  Defining scaffold geometries for interacting with proteins: geometrical classification of secondary structure linking regions.

Authors:  Tran T Tran; Christina Kulis; Steven M Long; Darryn Bryant; Peter Adams; Mark L Smythe
Journal:  J Comput Aided Mol Des       Date:  2010-09-23       Impact factor: 3.686

2.  Synthesis of a novel benzyl-octahydropyrazino[1,2-a]pyrimidin-6-one derivative as a convenient internal bicyclic peptidomimetic.

Authors:  Byoung J Min; Xuyuan Gu; Takashi Yamamoto; Ravil R Petrov; Hongchang Qu; Yeon Sun Lee; Victor J Hruby
Journal:  Tetrahedron Lett       Date:  2008-03-31       Impact factor: 2.415

3.  Preparation of diazabicyclo[4.3.0]nonene-based peptidomimetics.

Authors:  Craig A Hutton; Paul A Bartlett
Journal:  J Org Chem       Date:  2007-08-08       Impact factor: 4.354

4.  Synthesis of Chromeno[3,4-b]piperazines by an Enol-Ugi/Reduction/Cyclization Sequence.

Authors:  Ana Bornadiego; Ana G Neo; Carlos F Marcos
Journal:  Molecules       Date:  2021-02-27       Impact factor: 4.411
  4 in total

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