F De Riccardis1, F Johnson. 1. Department of Pharmacological Sciences, State University of New York at Stony Brook, 11794-3400, USA. dericca@unisa.it
Abstract
[reaction: see text] An efficient route to all of the possible cross-linked 2'-deoxypurines 1-3 has been developed by means of the Pd-mediated C-N bond formation in the key step. Utilizing this protocol, the synthesis of the first unnatural protected purine trimeric adduct 4 has been accomplished.
[reaction: see text] An efficient route to all of the possible cross-linked 2'-deoxypurines 1-3 has been developed by means of the n class="Chemical">Pd-mediated C-N bond formation in the key step. Utilizing this protocol, the synthesis of the first unnatural protected purine trimeric adduct 4 has been accomplished.
Authors: Paul F Thomson; Pallavi Lagisetty; Jan Balzarini; Erik De Clercq; Mahesh K Lakshman Journal: Adv Synth Catal Date: 2010-07-05 Impact factor: 5.837