The first O-NO bond energy scale in solution: heterolytic and homolytic cleavage enthalpies of O-nitrosyl carboxylate compounds

[reaction: see text] The first series of O-NO bond dissociation enthalpies was determined in solution for eight O-nitrosyl carboxylate compounds by direct titration calorimetry with a thermodynamic cycle. The derived bond energy data may serve as a quantitative guide to predict the NO binding and releasing abilities of the related amino acids.