Literature DB >> 10814296

Antimitotic diterpenes from Erythropodium caribaeorum test pharmacophore models for microtubule stabilization.

B Cinel1, M Roberge, H Behrisch, L van Ofwegen, C B Castro, R J Andersen.   

Abstract

[structure: see text] Six new antimitotic diterpenes, 2-7, have been isolated from the Caribbean octocoral Erythropodium caribaeorum. Structural variations encountered in this group of natural products test recently proposed pharmacophore models for microtubule stabilizing compounds.

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Year:  2000        PMID： 10814296     DOI： 10.1021/ol9912027

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  5 in total

Review 1.  Secondary Metabolites Isolated from Chilean Marine Algae: A Review.

Authors:  Dioni Arrieche; Héctor Carrasco; Andrés F Olea; Luis Espinoza; Aurelio San-Martín; Lautaro Taborga
Journal:  Mar Drugs       Date:  2022-05-23       Impact factor: 6.085

Review 2.  Biologically active marine natural products and their molecular targets discovered using a chemical genetics approach.

Authors:  David E Williams; Raymond J Andersen
Journal:  Nat Prod Rep       Date:  2019-11-21       Impact factor: 13.423

3.  Chemical screening method for the rapid identification of microbial sources of marine invertebrate-associated metabolites.

Authors:  Fabrice Berrue; Sydnor T Withers; Brad Haltli; Jo Withers; Russell G Kerr
Journal:  Mar Drugs       Date:  2011-03-21       Impact factor: 5.118

Review 4.  Marine Invertebrate Metabolites with Anticancer Activities: Solutions to the "Supply Problem".

Authors:  Nelson G M Gomes; Ramesh Dasari; Sunena Chandra; Robert Kiss; Alexander Kornienko
Journal:  Mar Drugs       Date:  2016-05-21       Impact factor: 5.118

5.  Metabolic Profiling of the Soft Coral Erythropodium caribaeorum (Alcyonacea: Anthothelidae) from the Colombian Caribbean Reveals Different Chemotypes.

Authors:  Sandra L Molina; Abel M Forero; Farja I Ayala; Mónica Puyana; Sven Zea; Leonardo Castellanos; Diego Muñoz; Gonzalo Arboleda; Adrián G Sandoval-Hernández; Freddy A Ramos
Journal:  Mar Drugs       Date:  2019-12-18       Impact factor: 5.118
  5 in total

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