Literature DB >> 10813008

Anaphylactoid reactions and angioedema during alteplase treatment of acute ischemic stroke.

M D Hill1, P A Barber, J Takahashi, A M Demchuk, T E Feasby, A M Buchan.   

Abstract

Among 105 patients given recombinant tissue plasminogen activator (rt-PA, alteplase) intravenously for acute stroke, 2 (1.9%) had lingual angioedema, which progressed to a fatal anaphylactoid reaction in 1. The authors review the 2 cases and possible mechanisms responsible. They warn that patients who are taking an angiotensin-converting-enzyme inhibitor may be at increased risk for angioedema with concomitant alteplase therapy.

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Year:  2000        PMID： 10813008      PMCID： PMC1232409     

Source DB:  PubMed          Journal:  CMAJ        ISSN： 0820-3946            Impact factor:   8.262


  22 in total

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Journal:  Br J Haematol       Date:  1991-04       Impact factor: 6.998

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3.  Comparison of dosage schedules of rt-PA in the treatment of proximal deep vein thrombosis.

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Journal:  J Lab Clin Med       Date:  1992-05

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Journal:  Br Heart J       Date:  1990-09

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Journal:  Lancet       Date:  1993-04-10       Impact factor: 79.321

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Journal:  Thromb Haemost       Date:  1990-10-22       Impact factor: 5.249

Review 7.  Anaphylactoid reaction during an infusion of recombinant tissue-type plasminogen activator for acute myocardial infarction.

Authors:  D Massel; J B Gill; J A Cairns
Journal:  Can J Cardiol       Date:  1991-09       Impact factor: 5.223

8.  A multicenter, randomized, placebo-controlled trial of a new form of intravenous recombinant tissue-type plasminogen activator (activase) in acute myocardial infarction.

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Journal:  J Am Coll Cardiol       Date:  1987-06       Impact factor: 24.094

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Journal:  Neurology       Date:  1992-09       Impact factor: 9.910

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Authors:  K Shimaya; H Sumi; M Maruyama; H Mihara
Journal:  Enzyme       Date:  1992
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  32 in total

1.  Reactions to alteplase in patients with acute thrombotic stroke.

Authors:  W B Chodirker
Journal:  CMAJ       Date:  2000-08-22       Impact factor: 8.262

2.  Angioedema after tPA: what neurointensivists should know.

Authors:  Jennifer E Fugate; Ejaaz A Kalimullah; Eelco F M Wijdicks
Journal:  Neurocrit Care       Date:  2012-06       Impact factor: 3.210

Review 3.  Clinical Presentation, Imaging, and Management of Complications due to Neurointerventional Procedures.

Authors:  Matthew C Davis; John P Deveikis; Mark R Harrigan
Journal:  Semin Intervent Radiol       Date:  2015-06       Impact factor: 1.513

4.  Perfluorocarbons enhance a T2*-based MRI technique for identifying the penumbra in a rat model of acute ischemic stroke.

Authors:  Graeme A Deuchar; David Brennan; Hugh Griffiths; I Mhairi Macrae; Celestine Santosh
Journal:  J Cereb Blood Flow Metab       Date:  2013-06-26       Impact factor: 6.200

5.  Rivaroxaban-Induced Hypersensitivity Syndrome.

Authors:  Charles-Olivier Chiasson; Arnaud Canneva; François-Olivier Roy; Maxime Doré
Journal:  Can J Hosp Pharm       Date:  2017-08-31

6.  Thrombolysis of a stroke patient with history of rtPA-associated angioedema.

Authors:  Felipe De Los Rios La Rosa; Amy K Starosciak; Brian Wolf
Journal:  Neurol Clin Pract       Date:  2017-12

7.  Airway management in a patient with severe angioedema after thrombolysis for ischemic stroke.

Authors:  Ivan Rocha Ferreira da Silva; Bernardo Boaventura Liberato
Journal:  Neurol Clin Pract       Date:  2012-09

Review 8.  Drug treatment of acute ischemic stroke.

Authors:  Sameer Bansal; Kiranpal S Sangha; Pooja Khatri
Journal:  Am J Cardiovasc Drugs       Date:  2013-02       Impact factor: 3.571

9.  [Orolingual angioedema under systemic thrombolysis with rt-PA: an underestimated side effect].

Authors:  C Ottomeyer; C Sick; M G Hennerici; K Szabo
Journal:  Nervenarzt       Date:  2009-04       Impact factor: 1.214

10.  Life-Threatening Anaphylactoid Reaction in an Acute Ischemic Stroke Patient With Intravenous rt-PA Thrombolysis, Followed by Successful Intra-Arterial Thrombolysis.

Authors:  In-Serk Park; A-Hyun Cho; Seung-Jae Lee; Joong-Seok Kim; Kwang-Soo Lee; Yeong-In Kim
Journal:  J Clin Neurol       Date:  2008-03-20       Impact factor: 3.077
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