Literature DB >> 10811528

The proinflammatory transcription factor NFkappaB: a potential target for novel therapeutical strategies.

P Renard1, M Raes.   

Abstract

NFkappaB is a ubiquitous transcription factor involved in the proinflammatory response to cytokines (such as IL-1 or TNF-alpha) and some particular stresses. The unraveling of the molecular mechanisms involved in its activation is quite recent, particularly in the case of IL-1-stimulated cells, but the identification of the molecules involved in this pathway opens new prospects in both pharmacological and toxicological research.

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Year:  1999        PMID： 10811528     DOI： 10.1023/a:1007652414175

Source DB:  PubMed          Journal:  Cell Biol Toxicol        ISSN： 0742-2091            Impact factor:   6.691


  16 in total

1.  Fluocinolone acetonide partially restores the mineralization of LPS-stimulated dental pulp cells through inhibition of NF-κB pathway and activation of AP-1 pathway.

Authors:  Zhongning Liu; Ting Jiang; Xinzhi Wang; Yixiang Wang
Journal:  Br J Pharmacol       Date:  2013-11       Impact factor: 8.739

Review 2.  Role of Notch and its oncogenic signaling crosstalk in breast cancer.

Authors:  Shanchun Guo; Mingli Liu; Ruben R Gonzalez-Perez
Journal:  Biochim Biophys Acta       Date:  2010-12-28

3.  The role of calcium, NF-κB and NFAT in the regulation of CXCL8 and IL-6 expression in Jurkat T-cells.

Authors:  Hazem Khalaf; Jana Jass; Per-Erik Olsson
Journal:  Int J Biochem Mol Biol       Date:  2013-09-13

4.  Immunostimulatory Effects of Cordyceps militaris on Macrophages through the Enhanced Production of Cytokines via the Activation of NF-kappaB.

Authors:  Seulmee Shin; Jeonghak Kwon; Sungwon Lee; Hyunseok Kong; Seungjeong Lee; Chong-Kil Lee; Kyunghae Cho; Nam-Joo Ha; Kyungjae Kim
Journal:  Immune Netw       Date:  2010-04-30       Impact factor: 6.303

5.  Plumbagin, a vitamin K3 analogue, abrogates lipopolysaccharide-induced oxidative stress, inflammation and endotoxic shock via NF-κB suppression.

Authors:  Rahul Checker; Raghavendra S Patwardhan; Deepak Sharma; Jisha Menon; Maikho Thoh; Santosh K Sandur; Krishna B Sainis; T B Poduval
Journal:  Inflammation       Date:  2014-04       Impact factor: 4.092

6.  Anti-inflammatory effects of ethanol extract from Kummerowia striata (Thunb.) Schindl on lps-stimulated RAW 264.7 cell.

Authors:  Jun-Yan Tao; Lei Zhao; Zhi-Jun Huang; Xiao-Yu Zhang; Shu-Ling Zhang; Qiong-Guang Zhang; Bao-Hui Zhang; Qi-Lin Feng; Guo-Hua Zheng
Journal:  Inflammation       Date:  2008-04-22       Impact factor: 4.092

7.  Influence of Kupffer cells on hepatic signal transduction as demonstrated by second messengers and nuclear transcription factors.

Authors:  Hong Ding; Jie-An Huang; Jing Tong; Xin Yu; Jie-Ping Yu
Journal:  World J Gastroenterol       Date:  2003-11       Impact factor: 5.742

Review 8.  Regulation of angiogenesis via Notch signaling in breast cancer and cancer stem cells.

Authors:  Weiqiang Zhou; Guangdi Wang; Shanchun Guo
Journal:  Biochim Biophys Acta       Date:  2013-10-30

9.  Urinary trypsin inhibitor attenuates lipopolysaccharide-induced neutrophil activation.

Authors:  Seong-Heon Lee; Hwi-Jin Kim; Hui-Jing Han; Mei Li; Sang-Hyun Kwak; Sanghee Park
Journal:  Korean J Anesthesiol       Date:  2012-12-14

10.  Immunomodulatory Effects of Dioscoreae Rhizome Against Inflammation through Suppressed Production of Cytokines Via Inhibition of the NF-κB Pathway.

Authors:  Seulah Kim; Seulmee Shin; Bobae Hyun; Hyunseok Kong; Shinha Han; Aeri Lee; Seungjeong Lee; Kyungjae Kim
Journal:  Immune Netw       Date:  2012-10-31       Impact factor: 6.303
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